青岛大学医学院学报2017,Vol.53Issue(5):532-533,536,3.DOI:10.13361/j.qdyxy.201705008
重复经颅磁刺激对精神分裂症病人认知功能的影响
EFFECT OF REPETITIVE TRANSCRANIAL MAGNETIC STIMULATION ON COGNITIVE FUNCTION IN PATIENTS WITH SCHIZOPHRENIA
摘要
Abstract
Objective To investigate the effect of repetitive transcranial magnetic stimulation (rTMS) on cognitive function in patients with schizophrenia.Methods A total of 76 patients with schizophrenia who were treated in our hospital in 2016 were enrolled,and according to the treatment modality,these patients were divided into treatment group and control group,with 38 patients in each group.The patients in the control group were given conventional antipsychotic medication,while those in the treatment group were given rTMS in addition to antipsychotic medication.The two groups were compared in terms of clinical outcome,change in cognitive function,and adverse reactions.Results After the treatment,the treatment group had a significantly higher overall response rate than the control group (x2 =4.37,P <0.05).Both groups had a significant improvement in the score of cognitive function after treatment,but the treatment group had a significantly greater improvement than the control group (t =2.94,P<0.05).The treatment group had a significantly lower incidence rate of adverse reactions than the control group (x2 =3.28,P<0.05).Conclusion In the treatment of schizophrenia,rTMS can improve cognitive function and reduce adverse reactions.关键词
精神分裂症/经颅磁刺激/认知Key words
schizophrenia/transcranial magnetic stimulation/cognition分类
医药卫生引用本文复制引用
范勇,赵蕾,孟祥军..重复经颅磁刺激对精神分裂症病人认知功能的影响[J].青岛大学医学院学报,2017,53(5):532-533,536,3.基金项目
青岛市卫生局医药科研计划项目(2013-WSZD097) (2013-WSZD097)