青岛大学医学院学报2017，Vol.53Issue(5)：562-564,3.DOI:10.13361/j.qdyxy.201705017
无抽搐电休克对精神分裂症病人认知及执行功能影响
EFFECTS OF MODIFIED ELECTROCONVULSIVE THERAPY ON COGNITIVE AND EXECUTIVE FUNCTION IN PATIENTS WITH SCHIZOPHRENIA
刘珊 1王凤娟 2杜衍晓3
作者信息
- 1. 青岛市精神卫生中心特检科,山东青岛266034
- 2. 青岛市肿瘤医院肿瘤防治中心
- 3. 青岛市中心医院口腔科
- 折叠
摘要
Abstract
Objective To explore the effects of modified electroconvulsive therapy (MECT) on cognitive and executive function in patients with schizophrenia.Methods A total of 90 patients with schizophrenia were randomly divided into control group and observation group.The patients in each group were given the same atypical antipsychotic monotherapy,and MECT was added to the observation group;the course of treatment was 6 weeks for both groups.Positive and Negative Syndrome Scale (PANSS),Wisconsin Card Sorting Test (WCST-64),Trail Making Test,and Digit Symbol Test were used to assess the patients in both groups before treatment and at the end of the 4th and 6th weeks of treatment.Results At the end of the 4th and 6th weeks of treatment,both groups showed significant reductions in the total and subscale scores of PANSS,and there were significant differences in these scores between the two groups (t =2.175-2.423,P ＜ 0.05).At the end of the 6th week of treatment,there were varying degrees of improvements in the scores of WCST-64,Trail Making Test A and B,and Digit Symbol Test,and there were significant differences between the two groups (t=2.160-2.960,P＜0.05).Conclusion MECT can effectively improve cognitive and executive function in patients with schizophrenia.关键词
电惊厥疗法/精神分裂症/认知/执行功能Key words
electroconvulsive therapy/schizophrenia/cognition/executive function分类
医药卫生引用本文复制引用
刘珊,王凤娟,杜衍晓..无抽搐电休克对精神分裂症病人认知及执行功能影响[J].青岛大学医学院学报,2017,53(5):562-564,3.
