摘要
Abstract
Objective To investigate the clinical effect of rivaroxaban versus low-molecular-weight heparin in the prevention of deep vein thrombosis (DVT) after surgery for femoral intertrochanteric fractures in elderly patients.Methods A retrospective analysis was performed for 120 elderly patients with femoral intertrochanteric fractures who were hospitalized in our hospital from July 2014 to July 2016,and according to the method for preventing DVT,these patients were divided into rivaroxaban group and low-molecular-weight heparin group,with 60 patients in each group.The two groups were compared in terms of coagulation parameters,intraoperative blood loss,postoperative visible blood loss,and incidence rate of DVT.Results There were no significant differences in coagulation parameters between the two groups at 1 day before surgery and at 1 and 10 days after surgery (P＞0.05).There were also no significant differences in intraoperative blood loss and postoperative visible blood loss between the two groups (P＞0.05).All patients were followed up for 3-12 months (mean 6 months),and there was a significant difference in the incidence rate of DVT between the rivaroxaban group and the low-molecular-weight heparin group (5.0 ％ vs 16.7％,x2 =4.227,P＜0.05).Conclusion Compared with low-molecular-weight heparin,rivaroxaban can reduce the incidence rate of DVT without increasing the risk of bleeding in the treatment of femoral intertrochanteric fractures in the elderly patients,and therefore,it holds promise for clinical application.关键词
利伐沙班/肝素,低分子质量/股骨骨折/静脉血栓形成/治疗结果Key words
rivaroxaban/heparin, low-molecular-weight/femoral fractures/venous thrombosis/treatment outcome分类
临床医学
