山东医药2018，Vol.58Issue(12)：14-17,4.DOI:10.3969/j.issn.1002-266X.2018.12.004
右肺上叶尖段及其亚段支气管CT定量参数对慢性阻塞性肺疾病病情的评估价值
Application value of quantitative CT in the apical segmental and the sub-segmental bronchi of right upper lobe for evaluating the condition of chronic obstructive pulmonary disease
摘要
Abstract
Objective To evaluate the application value of quantitative CT in the apical segmental and sub -segmental bronchi of right upper lobe for assessment of acute exacerbation of chronic obstructive pulmonary disease (COPD). Methods Thirty-one cases of COPD patients in acute exacerbation period and remission period with complete clinical data were selected.The airway wall thickness(WT),airway diameter ratio(TDR),airway wall area(WA)and the percentage of airway wall area accounting for the total cross-sectional area(WA%)of the apical segmental and sub-segmental bronchi of the right upper lobe were measured and calculated by multi-slice spiral CT(MSCT)on the same COPD patient in acute exacerbation period and remission period.The relationship between the four parameters and pulmonary function indexes (FEV1%and FEV1/FVC)was analyzed.Results TDR of the apical segmental bronchi of right upper lobe in the COPD patients in the acute exacerbation period was greater than that in the remission period(P<0.05), and WT,TDR, WA, WA%of the sub-segmental bronchi of the right upper lobe were greater than those in the remission period(P<0.05 or P<0.01).There was no correlation between WA %,WA,TDR,WT and FEV1%,FEV1/FVC in the apical segmental bron-chi of right upper lobe of patients in the acute exacerbation period and remission period(all P>0.05).In the sub-segmental bronchi of right upper lobe of patients,WA%was negatively correlated with FEV 1%(r=-0.425, -0.400,P<0.05), and TDR was negatively correlated with FEV 1%(r=-0.517, -0.473, both P<0.05).Conclusion Quantitative CT shows that the stenosis and wall thickening degree in the sub-segmental bronchi of right upper lobe are significantly higher than those in apical segmental bronchi of COPD patients in acute exacerbation period,and quantitative CT measurement could be helpful to identify COPD patients with acute exacerbation.关键词
慢性阻塞性肺疾病,急性加重期/多排螺旋CT,定量参数/右肺上叶尖段支气管Key words
chronic obstructive pulmonary disease/acute exacerbation/multi-slice spiral CT/quantitative parame-ter/apical segmental bronchus of right upper lobe分类
医药卫生引用本文复制引用
杨飞,纪蒙蒙,朱晓龙,王大伟,邹殿俊,王晓灿,崔书君..右肺上叶尖段及其亚段支气管CT定量参数对慢性阻塞性肺疾病病情的评估价值[J].山东医药,2018,58(12):14-17,4.基金项目
河北省科学技术研究与发展计划自筹经费项目(1421133D) （1421133D）
河北省医学科学研究重点课题计划(ZD20140476) （ZD20140476）
河北省医学科学研究重点课题指导计划项目(20170796). （20170796）
