陕西中医2018,Vol.39Issue(4):440-442,3.DOI:10.3969/j.issn.1000-7369.2018.04.010
小儿肺咳颗粒结合糖皮质激素治疗儿童肺炎临床研究
Clinical study of glucocorticoid combined with Xiao'er Feike granule in the treatment of children with pneumonia
摘要
Abstract
Objective:To study the clinical efficacy and safety of glucocorticoid combined with Xiao'er Feike granule in the treatment of pneumonia in children.Methods:112 cases of children with pneumonia was studied, which were randomly divided into experimental group and control group(n=56),control group used glucocorticoid treatment,experimental group gave Xiao'er Feike granule treatment on the basis of the control group,treatment for 2 weeks,the clinical curative effect,the children with pulmonary function(FEV1/FVC,PEF and MBC),inflammatory markers(IL-2,IL-6)and adverse reactions of 2 group were observed.Results:the total effective rate of the experi-mental group(96.4%)was significantly higher than the control group(78.6%),with statistical significance(P<0.05);FEV1/FVC,PEF and MBC of experimental group were significantly higher than the control group,with sta-tistical significance(P< 0.05);IL-2,IL-6 of experimental group was significantly lower than that of control group, with statistical significance(P< 0.05);2 groups had no nausea,headache,drowsiness,dry mouth,mild stuffy nose, chest tightness,heart palpitations,tremor,adverse reactions such as anaphylactic shock drugs.Conclusion:glucocor-ticoid combined with Xiao'er Feike granule in the treatment of children pneumonia in order to effectively improve the patient's lung function and ease the inflammatory response,safe and reliable关键词
肺炎/中西医结合疗法/糖皮质激素/@小儿肺咳颗粒Key words
Pneumonia/integrated Chinese traditional and western medicine therapy/Glucocorticoids/@Xiao'er Feike granule分类
医药卫生引用本文复制引用
贺孝良,侯小霞..小儿肺咳颗粒结合糖皮质激素治疗儿童肺炎临床研究[J].陕西中医,2018,39(4):440-442,3.基金项目
河南省卫生和计划委员会资助项目(15100321) (15100321)