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首页|期刊导航|陕西医学杂志|HE4、CA125和D-dimer检测在卵巢癌早期诊断筛查中的应用价值

HE4、CA125和D-dimer检测在卵巢癌早期诊断筛查中的应用价值

苏媛媛 李静 梁义娟

陕西医学杂志2018,Vol.47Issue(3):368-370,3.
陕西医学杂志2018,Vol.47Issue(3):368-370,3.DOI:10.3969/j.issn.1000-7377.2018.03.030

HE4、CA125和D-dimer检测在卵巢癌早期诊断筛查中的应用价值

Application value of HE4,CA125 and D-dimer in early diagnosis of ovarian cancer

苏媛媛 1李静 2梁义娟1

作者信息

  • 1. 河北大学附属医院妇产科,保定071000
  • 2. 河北省望都县中医医院妇产科,望都071000
  • 折叠

摘要

Abstract

Objective:To investigate the value of HE4,CA125and D-dimer in early diagnosis of ovarian canc-er.Methods:69 cases of patients with ovarian cancer(ovarian cancer group),65 cases of benign ovarian cyst pa-tients(benign group),another 63 cases of healthy women(healthy group),three groups of members of the serum HE4,CA125and D-dimer were compared,and analysis of diagnostic efficacy of single or combined detection of.Re-sults:the ovarian cancer group HE4,CA125and D-dimer levels were significantly higher than benign group and healthy group(P< 0.05),benign group the level of HE4was significantly higher than that of the control group(P< 0.05),no statistical significance in benign group and healthy group of CA 125and D-dimer level difference(P >0. 05).The combined detection sensitivity of CAI125+ HE4was 90.31%,higher than the HE488.93%,CA12573. 71% and D-dimer 64.89%,and the combined detection sensitivity of CAI125+ HE4+D-dimer was 94.87%,three was not only higher than the single detection,combined detection of CAI125+ HE4is higher than 90.31%.Conclu-sion:the combined detection of serum HE4,CA125and D-dimer can improve the accuracy of early screening for ovar-ian cancer,so as to improve the accuracy of diagnosis,which is of great significance for the early treatment and prognosis of ovarian cancer.

关键词

卵巢肿瘤/诊断/@附睾分泌蛋白质类/分/@CA-125抗原/@D二聚体

Key words

Ovarian neoplasms/diagnosis/Epididymal secretory/analysis/@CA125Antigen/@D-dimer

分类

医药卫生

引用本文复制引用

苏媛媛,李静,梁义娟..HE4、CA125和D-dimer检测在卵巢癌早期诊断筛查中的应用价值[J].陕西医学杂志,2018,47(3):368-370,3.

陕西医学杂志

1000-7377

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