生殖医学杂志2018，Vol.27Issue(3)：243-247,5.DOI:10.3969/j.issn.1004-3845.2018.03.010
盆腔手术及年龄对子宫内膜异位症患者辅助生殖妊娠结局的影响
Influence of pelvic surgery and age on pregnancy outcome of assisted reproductive technique in the patients with endometriosis
张莹莹 1杨洁 1肖国宏 1夏承来1
作者信息
- 1. 广州医科大学附属第三医院生殖医学中心,广东省生殖医学重点实验室,广东省普通高校生殖与遗传重点实验室,广东省产科重大疾病重点实验室,广州 510150
- 折叠
摘要
Abstract
Objective:To analyze influence of pelvic surgery and age on the pregnancy outcome of IVF/ICSI-ET in the patients with endometriosis(EMs).Methods:The data of 1 528 patients(a total of 2 659 cycles)with endometriosis in IVF/ICSI-ET treatment in the reproductive medicine center of the Third Affiliated Hospital of Guangzhou Medical University from May 15,2015 to February 28,2017 was took into retrospective analysis.Firstly,the EMs patients were divided into the group with pelvic surgery(n=1 123)and the group without pelvic surgery (n=405)according to whether there was a history of pelvic surgery before induced ovulation.And then,the EMs patients in pelvic surgery group and no pelvic surgery group were subdivided to ≤35 and ＞35 years old group respectively.The sex hormone levels and the clinical pregnancy outcome were compared among the groups.Results:Both of basic E2 and LH levels were not significantly different between pelvic surgery group and no pelvic surgery group.The basicFSH levels[(6.77+5.26)vs.(6.04+2.47)U/L] of patients in pelvic surgery group was significantly higher than those in the no pelvic surgery group(P＜0.05).The number of AFC [(12.38 + 6.61) vs.(12.98+ 6.53)] and the total clinical pregnancy rate (16.90％ vs.20.32％)in pelvic surgery group were significantly lower than those in no pelvic surgery group(P＜0.05).The basic FSH level was significantly lower,the E2,AFC and total clinical pregnancy rate was significantly higher in ≤35 years group than ＞35 years group in pelvic surgery group(all P＜ 0.05).Similarly,the basic FSH level was significantly lower,the AFC and total clinical pregnancy rate were significantly higher in ≤35 years group than ＞35 years group in no pelvic surgery group(all P＜ 0.05).Conclusions:IVF/ICSI-ET treatment for the patients with EMs undergoing should be as soon as possible(preferably ≤35 years of age),and pelvic surgery should be avoided as far as possible.If pelvic surgery is necessary,it is recommended that the surgery is performed after oocyte retrieved.关键词
子宫内膜异位症/盆腔手术/年龄/妊娠结局Key words
Endometriosis/Pelvic surgery/Age/Pregnancy outcome引用本文复制引用
张莹莹,杨洁,肖国宏,夏承来..盆腔手术及年龄对子宫内膜异位症患者辅助生殖妊娠结局的影响[J].生殖医学杂志,2018,27(3):243-247,5.
