烟草科技2018，Vol.51Issue(3)：62-71,10.
2-L-苏氨酸-2-脱氧-D-葡萄糖的合成、热裂解及抗氧化性能
Synthesis,pyrolysis and antioxidant activity of 2-L-threonine-2-deoxy-D-glucose
摘要
Abstract
In order to develop new cigarette flavors based on Heyns compounds,a Maillard reaction intermediate,2-L-threonine-2-deoxy-D-glucose(Thr-Glu),was synthesized from D-fructose(Fru)and L-threonine(Thr). The structure of the target product was characterized by IR,1H NMR,13C NMR and HRMS spectra. The thermal stability of the product was investigated by thermogravimetry-differential thermal analysis (TG-DTA)and online pyrolysis gas chromatography-mass spectroscopy(Py-GC/MS). The antioxidant activity of the product was tested with DPPH free radical scavenging assay and reducing capacity assay. The results showed that:1)The synthesized product was the target compound(Thr-Glu)with 99% purity,and the yield of 69.7%. 2)The initial pyrolysis temperature of Thr-Glu was 118.65 ℃,its total thermal mass loss reached about 80% up to 500 ℃. The number of pyrolytic products of Thr-Glu increased with the rise of temperature,and the major pyrolytic products were heterocyclic hydrocarbons,aldehydes,carboxylic acids,and ketones. Thr-Glu featured burnt-sweet,toasted,nutty,sweet,floral and creamy aroma. 3)Thr-Glu had a strong DPPH scavenging activity and reducing capacity,and was a potential antioxidant.关键词
2-L-苏氨酸-2-脱氧-D-葡萄糖(Thr-Glu)/卷烟/合成/热裂解/抗氧化Key words
2-L-Threonine-2-deoxy-D-glucose/Cigarette/Synthesis/Pyrolysis/Antioxidant activity分类
化学化工引用本文复制引用
武超伟,陈芝飞,赵永振,段鹍,霍娟,付瑜锋,何峰,芦昶彤..2-L-苏氨酸-2-脱氧-D-葡萄糖的合成、热裂解及抗氧化性能[J].烟草科技,2018,51(3):62-71,10.基金项目
河南中烟工业有限责任公司科技攻关项目"新型美拉德反应中间体的合成及应用技术研究"(YN2015002). （YN2015002）
