中国康复理论与实践2018，Vol.24Issue(3)：309-312,4.DOI:10.3969/j.issn.1006-9771.2018.03.012
双侧颈总动脉结扎致血管性痴呆大鼠模型研究进展
Progress in Vascular Dementia Rat Model Induced by Bilateral Common Carotid Artery Liga-tion(review)
摘要
Abstract
Rats after permanent bilateral common carotid artery ligation would result in cerebral blood flow reduction,learning and memory dysfunction,neuronal injury and death,synaptic and dendritic injury,and neuroinflammation,etc.,which repro-duce the pathology and clinical symptoms of human vascular dementia,that help for further research on pathophysiolo-gy and treatment of vascular dementia.关键词
血管性痴呆/双侧颈总动脉结扎/认知功能/神经元/突触/神经炎症/大鼠/综述Key words
vascular dementia/bilateral common carotid artery ligation/cognitive function/neuron/synapse/neuroin-flammation/rats/review分类
医药卫生引用本文复制引用
孟敏,李林..双侧颈总动脉结扎致血管性痴呆大鼠模型研究进展[J].中国康复理论与实践,2018,24(3):309-312,4.基金项目
北京市科技计划项目(No.Z131102002813066 （）
No.D0206001043191) （）
北京市高层次卫生技术人才计划(No.2011-1-7)Beijing Research and Development Plan(No.Z131102002813066 （No.2011-1-7）
No.D0206001043191)and Beijing Health High Level Professional Plan(No.2011-1-7) （No.2011-1-7）
