摘要
Abstract
Objective: To investigate the incidence, clinical features and echocardiographic characteristics of connective tissue disease(CTD) associated with pulmonary hypertention(PH). Methods: The ultrasonic cardiogram data of 1 729 CTD inpa-tients from June 2014 to December 2016 were collected. According to sPSP≥36 mmHg(1 mmHg≈0.133 kPa), PH patients were screened out and divided into group Ⅰ(sPAP<50 mmHg), group Ⅱ(sPAP: 50 mmHg~<70 mmHg), group Ⅲ (sPAP≥70 mmHg). Clinical and echocardiographic data of 138 suspected CTD-PH were analyzed retrospectively. Results: ①The incidence rate of PH in patients with CTD was about 8.0%. MCTD and SSc had the highest incidence of PH (30.8% and 10.5%). ②The inci-dence rate of pulmonary interstitial fibrosis, Raynaud's phenomenon and hyperuricemia were increased with the PH degree. ③PAD, RAD1, RAD2, RVD1, RVD2, RVD3 and RVD1/LVD were increased with the PH degree(P<0.05). Compared with former three groups, group Ⅲ had lower LVD1 (P<0.05). Compared with control group, group Ⅰ and group Ⅱ had higher LAD, group Ⅰ had higher LVD1 (P<0.05). PAD, RAD1, RAD2, RVD1, RVD2, RVD3 and RVD1/LVD2 were positively correlated with the degree of PH (P<0.001). Tricuspid valve regurgitation had the highest incidence of PH, followed by mitral and aortic valve regurgitation. The incidence of valvular stenosis and neoplasm were low. Conclusion: The incidence of PH in subgroups of CTD were different. Echocardiography is an important tool for screening PH patients. CTD-PH have a variety of reasons, we can assess the changes of cardiac structure and functions through echocardiography to identified the reasons.关键词
结缔组织病/高血压,肺性/超声心动描记术Key words
Connective tissue diseases/hypertension,pulmonary/Echocardiography分类
医药卫生
