中国全科医学2018，Vol.21Issue(11)：1336-1340,5.DOI:10.3969/j.issn.1007-9572.2017.00.158
复发性流产患者诊治流程图规范化的临床研究
Clinical Study of the Standardized Procedures for the Diagnosis and Treatment of Recurrent Spontaneous Abortion
摘要
Abstract
Objective To explore the effect of standardized procedures for the diagnosis and treatment of recurrent spontaneous abortion(RSA) in western Guangdong province,in order to promote the popularization of the procedures.Methods One hundred and eighty patients,who were diagnosed with RSA and treated in Reproductive Medicine Center,Affiliated Hospital of Guangdong Medical University from 2010 to 2016 were enrolled and equally divided into 6 groups based on their own willing:patients who had one,two,three or more RSAs and were willing to receive the diagnosis and treatment of RSA in accordance with the standardized procedures were assigned to groups A,B,C respectively,and those who had one,two,three or more RSAs but were not willing to accept the diagnosis and treatment of RSA in accordance with the standardized procedures were assigned to groups D,E,F,respectively.All of them were followed up for one year.The rate of successful pregnancy after treatment,RSA perception,satisfaction with the treatment and incidence of depression occurred in all the groups during the follow-up period were recorded.Results The rate of successful pregnancy after treatment did not differ significantly between groups A and D〔73.3%(22/30)vs 63.3%(19/30)〕(χ2=0.69,P>0.05).The rate of successful pregnancy after treatment was higher in group B than in group E〔66.7%(20/30)vs 36.7%(11/30)〕(χ2=5.41,P<0.05).Group C demonstrated higher rate of successful pregnancy after treatment than group F〔53.3%(16/30)vs 23.3%(7/30)〕(χ2=5.71,P<0.05). Groups A and D showed similar percentage of patients with RSA perception〔26.7%(8/30)vs 20.0%(6/30)〕(χ2=0.37, P>0.05).Group B had higher percentage of patients with RSA perception compared with group E〔63.3%(19/30)vs 33.3%(10/30)〕(χ2=5.41,P<0.05).Higher percentage of patients with RSA perception was found in group C instead of group F〔83.3%(25/30)vs 53.3%(16/30)〕(χ2=6.24,P<0.05).No significant difference in the level of satisfaction with treatment was found between groups A and D〔70.0%(21/30) vs 60.0%(18/30)〕 (χ2=0.66,P>0.05).Higher level of satisfaction with treatment was identified in group B rather than group E 〔73.3%(22/30) vs 43.3%(13/30)〕 (χ2=5.55, P<0.05).Compared with group F,group C had higher level of satisfaction with treatment〔63.3%(19/30)vs 33.3%(10/30)〕(χ2=5.41,P<0.05).Groups A and D were found with similar incidence of depression〔16.7%(5/30)vs 20.0%(6/30)〕(χ2=0.11,P>0.05).No obvious difference in the incidence of depression was observed between groups B and E〔23.3%(7/30) vs 30.0%(9/30)〕(χ2=0.34,P>0.05).Group C presented lower incidence of depression compared with group F〔26.7%(8/30)vs 56.7%(17/30)〕(χ2=5.55,P<0.05).Conclusion The standardization and popularization of the diagnosis and treatment for RSA will help to improve the level of satisfaction with treatment,raise the level of perception of the disease, reduce the incidence of depression and gain a better pregnancy outcome in these patients.关键词
流产,习惯性/流程图/治疗Key words
Abortion,habitual/Flow chart/Therapy分类
医药卫生引用本文复制引用
邹琳,何红华,庞小艳,彭彩玲,韦冰,许丽华..复发性流产患者诊治流程图规范化的临床研究[J].中国全科医学,2018,21(11):1336-1340,5.基金项目
2015年广东省公益研究与能力建设专项资金(2015A080803009) （2015A080803009）
2014年湛江市非资助科技攻关计划项目(2014B01088) （2014B01088）
