中国实用内科杂志2018，Vol.38Issue(2)：117-122,6.DOI:10.19538/j.nk2018020108
系统性肥大细胞增生症
Systemic mastocytosis
吴斌 1王恩第2
作者信息
- 1. 中国医科大学附属盛京医院血液内科,辽宁沈阳110022
- 2. Department of Pathology, Duke University Medical Center, Durham, NC, United States
- 折叠
摘要
Abstract
Mastocytosis is a heterogeneous disease,systemic mastocytosis is defined by compact multifocal mast cell infiltrates in bone marrow or extracutaneous tissues and other minor SM criteria,with or without skin involvement.The diagnosis of SM is difficult for complicated by hematologic nonmast cell lineage disease.In the updated WHO classification 2016,a new category is proposed.Tyrosine kinase inhibitors,multikinase inhibitor and antibody-drug conjugate may have potential efficacy in the treatment.关键词
系统性肥大细胞增生症/KIT突变/多重激酶抑制剂Key words
systemic mastocytosis/KIT mutation/multikinase inhibitor分类
医药卫生引用本文复制引用
吴斌,王恩第..系统性肥大细胞增生症[J].中国实用内科杂志,2018,38(2):117-122,6.
