摘要
Abstract
Objective To explore the epidemiological and pathogenic monitoring results of 128 patients with dengue. Method From August 2012 to December 2015, the clinical data of 128 dengue patients treated in our hospital were retrospectively analyzed, and their epidemiological characteristics were discussed. The viral nucleic acid and typing, specific antibodies IgG and IgM were detected. Result Dengue occurs at the age of 20 ~ 39 years old, accounting for 49.22%, the peak incidence in September; the incidence of dengue among the workers was significantly higher than that of other occupations (P<0.01); the incidence of dengue in patients with history of mosquito bites was significantly higher than that in patients without history of mosquito bites (P<0.01);the incidence of dengue in patients with contact history of fever patients was significantly higher than that of patients without contact history of fever (P<0.01). All patients had symptoms of fever, heat peak of 40.5℃, the average highest heat peak of 39.1℃, with irregular fever; 87 cases (67.97%) of patients with skin rash; loss of appetite in 92 cases (71.88%); 46 cases (35.94%) of nausea and vomiting; 27 cases (21.09%) of abdominal pain diarrhea. Detection acute dengue patients specimens IgM, IgG antibody in 128 cases, the results showed that IgM antibody positive in 112 cases, IgG antibody positive in 35 cases, the IgM antibodies in the IgG antibody positive were all positive. 128 cases of dengue were detected by nucleic acid, and there were 112 positive specimens. The proportion of DENV-1 type was significantly higher than that of other serotyping (P<0.01). Conclusion The incidence of dengue in Guangzhou is common with DENV-1 virus, and its clinical symptoms are typical. Early diagnosis and effective treatment are of great significance to improve the prognosis.关键词
登革热/流行病学/病原学Key words
Dengue/Epidemiology/Etiology
