中国卒中杂志2018，Vol.13Issue(3)：242-246,5.DOI:10.3969/j.issn.1673-5765.2018.03.009
缺血性卒中患者颅内外动脉狭窄与高血压、糖尿病的研究
Correlation of Intra-and Extracranial Arteriostenosis and Hypertension and Diabetes in Patients with Ischemic Stroke
逄锦晶 1宋丽艳 1徐丽红 1孙晓艳 1马宾宾1
作者信息
- 1. 261100 潍坊 潍坊市寒亭区人民医院神经内科
- 折叠
摘要
Abstract
Objective To investigate the characteristics of intra-and extracranial arteriostenosis in patients with ischemic stroke (IS) and its relationship with course and control levels of hypertension and diabetes. Methods The data of hospitalized patients with atherosclerotic acute ischemic stroke (AIS) who had intracranial and extracranial artery stenosis and concomitant hypertension or diabetes were retrospectively analyzed. Hypertension patients were divided into long-course group (>5 years) and short-course group (≤5 years), blood pressure well controlled and badly controlled groups. Diabetic patients were also divided into long-course group (>5 years) and short-course group (≤5 years), blood glucose well controlled group and badly controlled group. The distribution situation of intracranial and extracranial arteriostenosis and hemadostenosis degree were compared in different groups. Results A total of 216 patients with IS were enrolled into study, including 57 extracranial arteriostenosis patients, 105 intracranial arteriostenosis patients, and 54 intracranial and extracranial arteriostenosis patients. Among which, there were 73 mild arteriostenosis patients, 101 moderate arteriostenosis patients, 42 severe arteriostenosis and occlusion patients. There were 140 hypertensive patients in total. The commonest arterostenosis in long-course group was in intracranial artery (54.5%) and short-course group was in extracranial artery (51.3%), which had statistical significance in difference (P<0.001). Besides, the difference in the degree of arterial stenosis between two groups also had statistical significance. There were 76 diabetic patients in total. The commonest arterostenosis in long-course group was in intracranial artery (72.2%) and short-course group was in extracranial artery (65%), which had statistical significance in difference. The difference in the degree of arterial stenosis between two groups also had statistical significance. The probability of severe stenosis or occlusion in badly controlled hypertension group was higher than that of well controlled group(20.7% vs 8.6%).The probability of severe stenosis or occlusion in blood glucose badly controlled group was higher than that of well controlled group(40.9% vs 6.3%). Conclusion With the course of hypertension lengthening, the incidence of intracranial artery stenosis in IS patients was increasing, and moderate stenosis was the commonest. The proportion of severe stenosis or occlusion in blood pressure badly controlled patients was high. With the course progression of diabetes, the incidence of intracranial artery stenosis was increasing, and moderate stenosis was the commonest. Similarly, the proportion of severe stenosis or occlusion in blood glucose badly controlled group was high.关键词
动脉狭窄/缺血性卒中/高血压病/糖尿病Key words
Arteriostenosis/Ischemic Stroke/Hypertension/Diabetes引用本文复制引用
逄锦晶,宋丽艳,徐丽红,孙晓艳,马宾宾..缺血性卒中患者颅内外动脉狭窄与高血压、糖尿病的研究[J].中国卒中杂志,2018,13(3):242-246,5.
