动物营养学报2018，Vol.30Issue(4)：1238-1244,7.DOI:10.3969/j.issn.1006-267x.2018.04.005
过氧化物酶体增殖物激活受体调控幼龄反刍动物瘤胃的生酮作用及其机制
Peroxisome Proliferator?Activated Receptors: Regulation in Ketogenesis of Young Ruminants and Its Mechanisms
摘要
Abstract
A well?developed rumen is critical for young ruminants, not only for the health, but also for the production performance after grow up. There is no ketogenic function in rumen of new born young ruminants, the rumen morphology and function gradually mature with increasing of the days of age,and ketogenic function occurs. Ketogenesis is a key factor in rumen development and maturation, and beta?hydroxybutyric acid(BH?BA)is thought to be a mark of rumen development and maturation. Over the past decade, researchers have done a lot of researches on the factors that affect rumen ketogenesis,it has been found that peroxisome prolifer?ator?activated receptors(PPARs)are important for the proliferation of epithelial cells and ketogenesis. The ex?pression of 3?hydroxy?3?methylglutaryl coenzyme A synthase 2(HMGCS2)can be influenced by PPARs. But the current understanding of the mechanism of PPARs regulating ketogenesis remains unclear. This paper re?viewed the progress of PPARs regulating rumen development in young ruminants.关键词
过氧化物酶体增殖物激活受体/幼龄反刍动物/瘤胃/生酮作用/分子机制Key words
peroxisome proliferator⁃activated receptors/young ruminants/rumen/ketogenesis/molecular mechanism分类
农业科技引用本文复制引用
吕小康,王杰,刁其玉,张乃锋..过氧化物酶体增殖物激活受体调控幼龄反刍动物瘤胃的生酮作用及其机制[J].动物营养学报,2018,30(4):1238-1244,7.基金项目
国家公益性行业(农业)科研专项(201303143) （农业）
国家肉羊产业技术体系建设专项(CARS-39) （CARS-39）
