动物营养学报2018，Vol.30Issue(4)：1271-1278,8.DOI:10.3969/j.issn.1006-267x.2018.04.009
瘤胃上皮短链脂肪酸的吸收和代谢
Absorption and Metabolism of Short Chain Fatty Acids in Ruminal Epithelium
摘要
Abstract
Short chain fatty acids(SCFAs)are the important products of rumen fermentation, mainly inclu?ding acetate, propionate and butyrate, which are absorbed by ruminal epithelium and propionate enters the process of gluconeogenesis in liver for providing energy for body. With the increase of studies, it is found that SCFAs are transported by passive diffusion and transportation of specific transporters such as monocarboxylate/H+co?transporters(MCT),Na+/H+exchanger(NHE)and anion exchanger 2(AE2). SCFAs adsorption and transportation in ruminal epithelium is associated with pH in rumen lumen and ruminal epithelium cell. Trans?porters are working together to maintain the pH. After absorbed into cells, SCFA enter metabolism pathways mainly including synthesis of ketone body and cholesterol. Ketone body synthesis takes place in mitochondria, while cholesterol is synthesized in cytoplasm and endoplasmic reticulum. Both subtracts of pathways are 3?hy?droxy?3?methylglutaryl?CoA(HMG?CoA). Synthetic ketone body is transported out of cell and into extra tis?sues by MCT for energy supply. This article reviewed the adsorption and metabolism mechanisms of SCFAs to provide references for further study.关键词
瘤胃上皮/短链脂肪酸/吸收/代谢Key words
ruminal epithelium/short chain fatty acid/absorption/metabolism分类
农业科技引用本文复制引用
高景,齐智利..瘤胃上皮短链脂肪酸的吸收和代谢[J].动物营养学报,2018,30(4):1271-1278,8.基金项目
国家重点研发项目(2016YFD0500507) （2016YFD0500507）
湖北省科技支撑计划项目(2014BBA205) （2014BBA205）
大北农基金青年学者提升专项 （）
