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侵袭性真菌感染的药物应用调查分析

陆一纶 曹永兵

国际医药卫生导报2018,Vol.24Issue(8):1247-1250,4.
国际医药卫生导报2018,Vol.24Issue(8):1247-1250,4.DOI:10.3760/cma.j.issn.1007-1245.2018.08.037

侵袭性真菌感染的药物应用调查分析

Drugs for invasive fungal infection

陆一纶 1曹永兵2

作者信息

  • 1. 200433上海,第二军医大学学员旅学员11队
  • 2. 200433上海,第二军医大学药学院新药研究中心
  • 折叠

摘要

Abstract

Objective To provide some references for the rational use of antifungal drugs by summarizing the characteristics,mechanism,adverse reactions,and drug resistance of antifungal drugs for injection.Methods The related data were searched from related literatures,works,and China National Knowledge Infrastructure and VIP databases and statistically analyzed.Results There were 741 clinical reports about the treatment of fungal infections,including 250 theses about treatment for invasive fungal infection.Among the 250 theses,73 theses (29.2%) had used polyene drugs,210 (84.0%) triazole,17 (6.8%) flurocytosine,and 33 (13.2%) pneumocandins.Conclusions The application of antifungal drugs are more and more widely used;the third generation of azole drugs and fluroeytosine drugs have become the first-line treatment drugs for deep fungal infections,especially for life threatening systemic fungus,aspergillus,and candida infections.

关键词

侵袭性真菌感染/调查/用药选择

Key words

Invasive fungal infection/Survey/Drug selection

引用本文复制引用

陆一纶,曹永兵..侵袭性真菌感染的药物应用调查分析[J].国际医药卫生导报,2018,24(8):1247-1250,4.

国际医药卫生导报

1007-1245

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