医学分子生物学杂志2018，Vol.15Issue(1)：57-62,6.DOI:10.3870/j.issn.1672-8009.2018.01.012
支持细胞信号通路在精子发生减数分裂调节中的作用
Role of Sertoli Cell Signaling Pathway in the Regulation of Meiosis in Spermatogenesis
摘要
Abstract
Meiosis is important for spermatogenesis and it ensures the stability of genetic infor-mation.Sertoli cells are the only somatic cells in the seminiferous tubule,which interact directly with spermatogonia and regulate the meiosis of spermatocytes by secreting the paracrine factors.In recent years,studies have demonstrated that follicle-stimulating hormone(FSH),retinoic acid(RA),an-drogen play important roles in meiosis.Here, we review how these substances regulate meiosis through the mediation of Sertoli cell in an attempt to provide ideas and inspirations for the following studies on the role of Sertoli cells in the regulation of spermatocyte meiosis.关键词
支持细胞/精子发生/减数分裂/信号通路Key words
sertoli cell/spermatogenesis/meiosis/signaling pathway分类
医药卫生引用本文复制引用
余跃进,黄东晖..支持细胞信号通路在精子发生减数分裂调节中的作用[J].医学分子生物学杂志,2018,15(1):57-62,6.基金项目
华中科技大学自主创新基金(No.0118519028,No.0118519013) （No.0118519028,No.0118519013）
This work was supported by a grant from the Independent Innovation Foundation of the Medical College of Huazhong University of Science and Technology(No.0118519028,No.0118519013) （No.0118519028,No.0118519013）
