神经损伤与功能重建2018，Vol.13Issue(2)：62-65,4.DOI:10.16780/j.cnki.sjssgncj.2018.02.003
影响中青年急性缺血性卒中脑血管狭窄的危险因素研究
The Risk Factors for Acute Ischemic Stroke in Young and Middle-aged Patients with Cerebro-Vascular Stenosis
摘要
Abstract
Objective:To study the risk factors for acute ischemic stroke in middle-aged and young patients with cerebrovascular stenosis in Xinjiang.Methods:Clinical data of 130 middle-aged and young patients with acute ischemic stroke were collected.Cases were divided into the cerebrovascular stenosis group (n=64) and the no cerebrovascular stenosis group (n=66).Stenosis group was further divided into mild stenosis group (n=16),moderately severe stenosis group (n=17),and occlusion group (n=31).Data was collected on patient serum levels of triglyceride (TG),low-density lipoprotein cholesterol (LDL-C),total cholesterol (TC),high density lipoprotein cholesterol (HDL-C),TC/HDL-C,TG/HDL-C,LDL-C/HDL-C,as well as history of high blood pressure,history of diabetes,and BMI.Data was analyzed for correlation between serum lipid index and degree of cerebrovascu lar stenosis,and analysis of risk factors for cerebrovascular stenosis was performed.Results:Hypertension of ≥10 years,TC,and TC/HDL-C were significantly different between the cerebrovascular stenosis group and no cerebrovascular stenosis group (P＜0.05).TC and TC/HDL-C were positively correlated with cerebrovascular ste nosis degree (P＜0.01).Serum TC level and TC/HDL-C were significantly lower in the moderate and mild stenosis groups than in the occlusion group (P＜0.05).Hypertension of ≥ 10 years and TC/HDL-C were independent risk factors for middle-aged and young patients of ischemic stroke with cerebrovascular stenosis (P＜0.05).Conclusion:Serum TC and TC/HDL-C were closely related with degree of cerebrovascular stenosis in middle-aged and young patients of acute ischemic stroke in Xinjiang.Hypertension of ≥ 10 years and TC/HDL-C can thus be considered risk factors for middle-aged and young acute ischemic stroke with cerebrovascular stenosis.关键词
中青年/缺血性卒中/头颈CT血管成像/数字减影血管造影/危险因素Key words
middle-age and young/ischemic stroke/head and neck CT/angiography, digital subtraction/risk factor分类
医药卫生引用本文复制引用
葛晓敏,杜磊,马建华..影响中青年急性缺血性卒中脑血管狭窄的危险因素研究[J].神经损伤与功能重建,2018,13(2):62-65,4.基金项目
国家自然科学基金(No.81060097) （No.81060097）
