广西医科大学学报2018,Vol.35Issue(3):328-330,3.DOI:10.16190/j.cnki.45-1211/r.2018.03.012
miR-518b在稽留流产患者绒毛组织及血清中的表达及其意义
The expression of miR-518b in villous tissues and serum of patients with missed abortion and its clinical significance
摘要
Abstract
Objective:To investigate the expression of microRNA518b (miR-518b) in villous tissues and serum of patients with missed abortion and its clinical significance.Methods:Villous tissues and serum samples from 30 cases of missed abortion and 30 cases of early pregnancy abortion were collected.The expression of miR-518b was determined by real-time fluorescent quantitative PCR (qPCR).Results:The expression level of miR-518b in villous tissues and serum of patients with missed abortion was significantly increased,compared with the controls (P<0.01).Conclusion:Upregulation of miR-518b expression in villous tissues and serum might be associated with the occurrence of missed abortion.关键词
miR-518b/稽留流产/绒毛Key words
miR-518b/missed abortion/villi分类
医药卫生引用本文复制引用
植枝福,杨文梅,周卓琳,庞丽红..miR-518b在稽留流产患者绒毛组织及血清中的表达及其意义[J].广西医科大学学报,2018,35(3):328-330,3.基金项目
国家自然科学基金资助项目(No.81660256) (No.81660256)
广西壮族自治区教育厅中青年教师基础能力提升项目(No.KY2016LX032) (No.KY2016LX032)