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首页|期刊导航|广西医科大学学报|miR-518b在稽留流产患者绒毛组织及血清中的表达及其意义

miR-518b在稽留流产患者绒毛组织及血清中的表达及其意义

植枝福 杨文梅 周卓琳 庞丽红

广西医科大学学报2018,Vol.35Issue(3):328-330,3.
广西医科大学学报2018,Vol.35Issue(3):328-330,3.DOI:10.16190/j.cnki.45-1211/r.2018.03.012

miR-518b在稽留流产患者绒毛组织及血清中的表达及其意义

The expression of miR-518b in villous tissues and serum of patients with missed abortion and its clinical significance

植枝福 1杨文梅 1周卓琳 1庞丽红1

作者信息

  • 1. 广西医科大学第一附属医院,南宁 530021
  • 折叠

摘要

Abstract

Objective:To investigate the expression of microRNA518b (miR-518b) in villous tissues and serum of patients with missed abortion and its clinical significance.Methods:Villous tissues and serum samples from 30 cases of missed abortion and 30 cases of early pregnancy abortion were collected.The expression of miR-518b was determined by real-time fluorescent quantitative PCR (qPCR).Results:The expression level of miR-518b in villous tissues and serum of patients with missed abortion was significantly increased,compared with the controls (P<0.01).Conclusion:Upregulation of miR-518b expression in villous tissues and serum might be associated with the occurrence of missed abortion.

关键词

miR-518b/稽留流产/绒毛

Key words

miR-518b/missed abortion/villi

分类

医药卫生

引用本文复制引用

植枝福,杨文梅,周卓琳,庞丽红..miR-518b在稽留流产患者绒毛组织及血清中的表达及其意义[J].广西医科大学学报,2018,35(3):328-330,3.

基金项目

国家自然科学基金资助项目(No.81660256) (No.81660256)

广西壮族自治区教育厅中青年教师基础能力提升项目(No.KY2016LX032) (No.KY2016LX032)

广西医科大学学报

OACSTPCD

1005-930X

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