哈尔滨商业大学学报（自然科学版）2018，Vol.34Issue(2)：134-137,4.
中药复方对大鼠肾小球系膜细胞作用的影响
Effect of Chinese herbal compound on glomerular mesangial cells in rats
摘要
Abstract
The effect of Chinese herbal compound on rat glomerular mesangial cells(MsC) was observed to explore the effect of traditional Chinese medicine on prevention and treatment of chronic renal failure(CRF)from cell biology level.The effect of Chinese herbal com-pound on rat glomerular mesangial cells was observed by MTT colorimetric method.The re-sults showed that traditional Chinese medicine compound could inhibit the proliferation of rat glomerular mesangial cells in vitro,and its inhibitory degree was related to the concentration of drug,and the time of drug action is with the increase of drug concentration.The inhibition rate of mesangial cell proliferation also increased accordingly.The inhibitory effect of Chi-nese herbal compound on the proliferation of rat glomerular mesangial cells in vitro was posi-tively correlated with the concentration and time of serum in serum.Chinese medicine com-pound inhibition of glomerular mesangial cell proliferation is one of the important mechanisms to prevent the development of glomerulosclerosis.关键词
肾小球系膜细胞/中药复方/细胞培养/作用影响Key words
glomerular mesangial cells/traditional Chinese medicine compound/cell cul-ture/effect分类
医药卫生引用本文复制引用
张翠,张腾娇,张思琪,王丹枫,孙博..中药复方对大鼠肾小球系膜细胞作用的影响[J].哈尔滨商业大学学报（自然科学版）,2018,34(2):134-137,4.基金项目
黑龙江省自然科学基金项目(D201147) （D201147）
黑龙江省教育厅基金项目(11531451) （11531451）
哈尔滨商业大学研究团队支持项目(2016TD008) （2016TD008）
哈尔滨商业大学研究生创新科研项目(YJSCX2017-445HSD). （YJSCX2017-445HSD）
