检验医学与临床2018,Vol.15Issue(7):900-902,3.DOI:10.3969/j.issn.1672-9455.2018.07.002
探讨高龄体外受精患者温和刺激方案中生长激素预处理的疗效
Investigation of the application of growth hormone with the mild stimulus protocol to the elderly patients during in vitro fertilization
摘要
Abstract
Objective To inverstigate on the application of growth hormone with the mild stimulus protocol to the elderly patients during in vitro fertilization(IVF).Methods A total of 80 infertile elderly patients on the mild stimulus protocol accepted IVF treatment were randomly divided into treatment group(n=40)and control group(n=40).The treatment group was treated with growth hormone(4.5 U)from the 6-7 day.The control group did not use growth hormone throughout the course.The average number of eggs,the transplan-tation rate,the normal fertilization rate and the clinical pregnancy rates were observed in the two groups.Re-sults There were statistically significant differences in the cancellation rate of oocyte retrieval(2.50% vs. 20.00%)and the cancellation rate of embryo transfer(5.00% vs.25.00%)(P<0.05).The high quality embryo rates(41.09% vs.22.80%)and the clinical pregnancy rates(47.36% vs.23.33%)were statistically higher than the control group(P<0.05).Conclusion The application of growth hormone to the elderly IVF patients could increase the clinical pregnancy rates.关键词
生长激素/体外受精/妊娠结局/高龄患者Key words
grow th hormone/in vitro fertilization/pregnancy outcome/elderly patient分类
医药卫生引用本文复制引用
张潇潇,吕群..探讨高龄体外受精患者温和刺激方案中生长激素预处理的疗效[J].检验医学与临床,2018,15(7):900-902,3.基金项目
四川省科技支撑计划资助项目(2011SZ0136). (2011SZ0136)