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探讨高龄体外受精患者温和刺激方案中生长激素预处理的疗效

张潇潇 吕群

检验医学与临床2018,Vol.15Issue(7):900-902,3.
检验医学与临床2018,Vol.15Issue(7):900-902,3.DOI:10.3969/j.issn.1672-9455.2018.07.002

探讨高龄体外受精患者温和刺激方案中生长激素预处理的疗效

Investigation of the application of growth hormone with the mild stimulus protocol to the elderly patients during in vitro fertilization

张潇潇 1吕群1

作者信息

  • 1. 四川省医学科学院·四川省人民医院生殖中心,成都610072
  • 折叠

摘要

Abstract

Objective To inverstigate on the application of growth hormone with the mild stimulus protocol to the elderly patients during in vitro fertilization(IVF).Methods A total of 80 infertile elderly patients on the mild stimulus protocol accepted IVF treatment were randomly divided into treatment group(n=40)and control group(n=40).The treatment group was treated with growth hormone(4.5 U)from the 6-7 day.The control group did not use growth hormone throughout the course.The average number of eggs,the transplan-tation rate,the normal fertilization rate and the clinical pregnancy rates were observed in the two groups.Re-sults There were statistically significant differences in the cancellation rate of oocyte retrieval(2.50% vs. 20.00%)and the cancellation rate of embryo transfer(5.00% vs.25.00%)(P<0.05).The high quality embryo rates(41.09% vs.22.80%)and the clinical pregnancy rates(47.36% vs.23.33%)were statistically higher than the control group(P<0.05).Conclusion The application of growth hormone to the elderly IVF patients could increase the clinical pregnancy rates.

关键词

生长激素/体外受精/妊娠结局/高龄患者

Key words

grow th hormone/in vitro fertilization/pregnancy outcome/elderly patient

分类

医药卫生

引用本文复制引用

张潇潇,吕群..探讨高龄体外受精患者温和刺激方案中生长激素预处理的疗效[J].检验医学与临床,2018,15(7):900-902,3.

基金项目

四川省科技支撑计划资助项目(2011SZ0136). (2011SZ0136)

检验医学与临床

1672-9455

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