肿瘤预防与治疗2017，Vol.30Issue(6)：465-469,5.DOI:10.3969/j.issn.1674-0904.2017.06.013
辣椒素预防及抗肿瘤作用机制研究进展
Tumor Prevention and Anti-carcinogenic Mechanism of Capsaicin
左明 1胡丽贞1
作者信息
- 1. 610041成都,四川省肿瘤医院·研究所,四川省癌症防治中心,电子科技大学医学院临床营养中心
- 折叠
摘要
Abstract
Numerous studies are focused on the application of active compounds in natural fruits and vegetables for prevention and treatment of tumor.Capsaicin has the prevention and the anti-tumor effect,which is a kind of alkaloid found in pepper cortex.Mechanism of its anti-tumor effect is complex.It cause cell cycle arrest,metabolic inhibition,tumor necrosis,apoptosis and autophagy,anti-angiogenesis and reduce the metastasis of cancer cells mainly by targeting at the activation of capsaiein receptor or through other signaling pathways.Capsaicin has the anti-tumor effect on kinds of tumor so that capsaicin could be used as a potential drug for cancer prevention and treatment,especially in combination with other anticancer drugs.There would be wide application prospect.In this paper,the research progress of capsaicin prevention and anti-tumor mechanism is discussed.关键词
辣椒素/辣椒素受体/恶性肿瘤/预防/治疗Key words
capsaicin/capsaicin receptor/malignant tumor/prevention/treatment分类
医药卫生引用本文复制引用
左明,胡丽贞..辣椒素预防及抗肿瘤作用机制研究进展[J].肿瘤预防与治疗,2017,30(6):465-469,5.
