山东医药2018，Vol.58Issue(6)：15-18,4.DOI:10.3969/j.issn.1002-266X.2018.06.004
年龄对冠心病合并2型糖尿病患者经皮冠状动脉介入治疗预后的影响
Effects of age on the prognosis of patients with coronary heart disease complicated with type 2 diabetes mellitus after percutaneous coronary intervention
摘要
Abstract
Objective To investigate the effects of age on the prognosis of patients with coronary heart disease complicated with type 2 diabetes mellitus after treatment of percutaneous coronary intervention (PCI).Methods Patients with coronary heart disease complicated with type 2 diabetes mellitus (n =705) who underwent PCI therapy were divided into three groups according to their age:youth group (aged 18-59 years),old group (aged 60-74 years),and elderly group (aged ≥75 years).The clinical data were collected.All-cause death and major adverse cardiac events (cardiac death,unplanned revascularization,nonfatal myocardial infarction) were followed up after PCI therapy.COX regression model was used to investigate the prognostic evaluation of age.Results The ratios of male patients,previous history of smoking,and insulin use were lower in the elderly group than those of the youth group and old group,and the elderly group had higher ratios of previous history of hypertension and higher level of serum creatinine (all P ＜ 0.05).About the distribution of coronary disease,the single-vessel disease was higher in the youth group,2-vessel disease was higher in the elderly group,and the old group had a higher proportion of severe calcification lesion (all P ＜ 0.01).There was no significant difference in the incidence of all-cause death,cardiac death,nonfatal myocardial infarction,and unplanned revascularization between the three groups.COX regression model showed that age was not significantly correlated with all-cause mortality and major adverse cardiac events.Conclusion Age is not a predictor of adverse cardiovascular events after PCI in patients with coronary heart disease complicated with type 2 diabetes mellitus.关键词
冠心病/2型糖尿病/经皮冠状动脉介入治疗/年龄Key words
coronary heart disease/type 2 diabetes mellitus/percutaneous coronary intervention/age分类
医药卫生引用本文复制引用
焦云娣,于彤彤,王卓,孙志军,孙兆青..年龄对冠心病合并2型糖尿病患者经皮冠状动脉介入治疗预后的影响[J].山东医药,2018,58(6):15-18,4.基金项目
辽宁省科技厅社会发展攻关计划(2011225020). （2011225020）
