摘要
Abstract
Objective:To explore the curative effect of reduning injection combined with zinc gluconate in the treatment of infantile diarrhea and its effect on cellular immunity.Methods:A total of 102 cases of patients with infantile diarrhea in our hospital were selected and randomly divided into the treatment group (n =51) and the control group (n =51).The control group was treated with montmorillonite powder,and treatment group was treated with reduning injection combined with zinc gluconate.Clinical curative effect,clinical performance,immune index of 2 groups were compared.Results:The total clinical effective rate of the control group was 76.47％,which was significantly lower than 90.20％ of the treatment group (P ＜ 0.05);there was no significant difference in stool frequency between 2 groups (P ＞ 0.05).The stool recovery time of the control group was longer than the treatment group (P ＜0.05);Compared with that before treatment,red cell C3b receptor rosette (RC3bRR),the red blood cell immune complex rosette (RICR),rosette forming enhancement rate (RFER) of 2 groups after treatment were significantly increased,and rosette forming inhibitor rate (RFIR) was significantly decreased (P ＜ 0.05 or P ＜ 0.01) with significant difference between 2 groups (P ＜ 0.05 or P ＜ 0.01);Compared with that before treatment,the ratio of CD3 +,CD4 + and CD4 +/CD8 + of 2 groups after treatment were significantly increased (P ＜ 0.05 or P ＜ 0.01),and the treatment group was higher than the control group (P ＜ 0.05 or P ＜ 0.01).There was no significant difference of CD8 + between 2 groups before and after treatment (P ＞ 0.05);Compared with that before treatment,the levels of serum immunoglobulin A (IgA),immunoglobulin G (IgG),fecal secretory IgA (sIgA) of 2 groups after treatment were significantly increased (P ＜ 0.01),and the treatment group was higher than the control group (P ＜ 0.05 or P ＜ 0.01).Conclusion:Reduning injection combined with zinc gluconate in the treatment of infantile diarrhea can improve the clinical symptom and immune function,with remarkable curative effect,which is worthy of promotion.关键词
小儿腹泻/热毒宁/葡萄糖酸锌/疗效/免疫功能Key words
Infantile diarrhea/Reduning injection/Zinc gluconate/Curative effect/Immunologic function分类
医药卫生
