世界中医药2017，Vol.12Issue(11)：2779-2782,4.DOI:10.3969/j.issn.1673-7202.2017.11.054
紫甘蓝提取液对人乳腺癌细胞生长和迁移的抑制作用
Purple Cabbage Extract in Inhibition of Breast Cancer Cell Growth and Migration
摘要
Abstract
Objective:To investigate the effect of purple cabbage extract (PCE) on breast cancer cell MCF7growth and migration.Methods:The inhibition rate of MCF7 cells was assessed by MTT method,and the inverted phase contrast microscope was used to observe the cellular shape.Flow cytometry was utilized for measuring cell apoptosis after Annexin V-FITC/PI stained the cell.The transwell chamber was used to investigate cell migration.Results:PCE inhibited MCF7 cell proliferation in a concentration-and time-dependent manner (P ＜ 0.05).After incubated with PCE,the cells became shrinkage and turned round,arranged loosely and adhered not favorable gradually.PCE induced MCF7 cell apoptosis and inhibited cell migration in a concentration-dependent manner (P ＜ 0.05).Conclusion:PCE inhibits breast cancer cell MCF7 growth and migration.关键词
紫甘蓝/乳腺癌/细胞增殖/细胞凋亡/细胞迁移Key words
Purple cabbage/Breast cancer/Cell proliferation/Cell apoptosis/Cell migration分类
医药卫生引用本文复制引用
徐颖倩,曾雪,唐倩..紫甘蓝提取液对人乳腺癌细胞生长和迁移的抑制作用[J].世界中医药,2017,12(11):2779-2782,4.基金项目
重庆医药高等专科学校科研计划项目(ygz2015107) （ygz2015107）
