世界中医药2017，Vol.12Issue(11)：2786-2790,5.DOI:10.3969/j.issn.1673-7202.2017.11.056
陈皮精准煮散饮片与市售饮片的质量
Comparative Study on Quality of Precise Powder Decoction Pieces of Citri Retilulatae Pericarpium with its Crude Slices
摘要
Abstract
Objective:To evaluate the quality difference of precise powder decoction pieces (PPDP) of Citri Retilulatae Pericarpium (CRP) and traditional commercial crude slices.Methods:Different specifications of PPDP were prepared,their dry extract contents were compared with those of commercial slices.Three batches of commercial slices were collected,and the content uniformity,fingerprint and similarity were evaluated before and after mixing and preparation by HPLC-DAD and DNA sequence alignment.Results:Paste rate of PPDP was slightly higher than that of the traditional commercial slices,among which paste rate of 5-10 mesh were the highest.The dissolution rate of hesperidin of PPDP was higher than that of traditional commercial slices.RSD of inter-assay dissolution of commercial slices was 18.93％,which could be reduced to 6.28 ％ after being mixed and prepared into PPDP.Conclusion:PPDP and traditional commercial slices of CRP shared consistent properties,while PPDP could apparently improve the extraction rate,the dissolution rate and the quality uniformity,which demonstrates boiled powder of CRP is more suitable in clinical practice.关键词
陈皮/精准煮散饮片/DNA条形码/指纹图谱Key words
Citri Retilulatae Pericarpium/Precise powder decoction pieces/DNA/Fingerprint分类
医药卫生引用本文复制引用
莫结丽,张靖,宫璐,丘小惠,肖水明,李西文,徐江,黄志海..陈皮精准煮散饮片与市售饮片的质量[J].世界中医药,2017,12(11):2786-2790,5.基金项目
广东省药品检验所专项(2016KT1014) （2016KT1014）
广东省中医院专项(2015KT1817) （2015KT1817）
国家自然基金项目(81402887) （81402887）
中国中医科学院中医药健康服务专项(ZZ0908067) （ZZ0908067）
