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超声引导下微波消融单次治疗多发甲状腺结节的疗效和安全性评估

徐萍 徐岷 葛璐 陈宝定

实用医学杂志2018,Vol.34Issue(1):96-99,4.
实用医学杂志2018,Vol.34Issue(1):96-99,4.DOI:10.3969/j.issn.1006-5725.2018.01.024

超声引导下微波消融单次治疗多发甲状腺结节的疗效和安全性评估

Evaluating the effect and safety of treating thyroid multiple-nodule by Ultrasound-guided microwave ablation in one-session

徐萍 1徐岷 2葛璐 2陈宝定3

作者信息

  • 1. 江苏大学附属医院内分泌科,江苏镇江212001
  • 2. 江苏大学附属医院消化科,江苏镇江212001
  • 3. 江苏大学附属医院超声科,江苏镇江212001
  • 折叠

摘要

Abstract

Objective To investigate the short-term efficacy of treating thyroid multiple-nodule by Ultrasound-guided microwave ablation in one-session,and to evaluate its safety and effect.Methods Treatment and follow-up data of 85 patients with benign thyroid nodules underwent tUltrasound-guided microwave ablation in one-session were retrospectively analyzed.Results Symptom scores and cosmetic scores increased with the increasing number of nodules ablated before ablation (P < 0.001),as well as the ablation time (P < 0.001).However,there was no significant difference in the amount of isolation belt and intraoperative pain score between the groups.There were no serious complications such as recurrent laryngeal nerve injury and massive hemorrhage in 85 cases underwent tUltrasound-guided microwave ablation in one-session.Compared with the thyroid function,there was no significant difference on before the ablation and 1,3,6 months after ablation.Postoperative 6 months,the maximum volume of nodule and the total volume of the nodules were reduced 63% and 69.5%,respectively.After ablation,both the symptom scores and cosmetic scores were improved significantly.On 6 months after ablation,the symptom scores decreased from (4.41 ± 1.75) cm to (1 ± 0.76) cm,and the cosmetic score3 decreased from 2.27 ± 0.81 to 1.25 ± 0.43.Conclusion Ultrasound-guided microwave ablation could treat multiple thyroid nodules effectively and protect the physiological function of thyroid,which was worthy of further promotion in clinical application.

关键词

微波消融/甲状腺结节/症状性结节/生理功能

Key words

microwave ablation/thyroid nodule/symptomatic nodule/physiological function

引用本文复制引用

徐萍,徐岷,葛璐,陈宝定..超声引导下微波消融单次治疗多发甲状腺结节的疗效和安全性评估[J].实用医学杂志,2018,34(1):96-99,4.

基金项目

镇江市2015年度第四批科技计划(社会发展)项目(编号:SH2015075) (社会发展)

国家自然科学基金项目(编号:81672402) (编号:81672402)

实用医学杂志

OA北大核心CSTPCD

1006-5725

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