实用医学杂志2018，Vol.34Issue(6)：987-990,4.DOI:10.3969/j.issn.1006-5725.2018.06.028
甲状腺乳头状癌中PRL-3表达与肿瘤相关巨噬细胞及淋巴管生成的相关性
Expression and relationship of PRL-3,tumor associated macrophags and lymphangiogenesis in papillary thyroid carcinoma
摘要
Abstract
Objective To investigate the relationship of PRL-3,tumor associated macrophages and lym-phangiogenesis in papillary thyroid carcinoma. Methods SP immunohistochemistry was used to study the levels of PRL-3,CD68,and D2-40 in papillary thyroid carcinoma and thyroid adenoma.Results The positive expression rates of PRL-3,CD-68 and D2-40 were higher in papillary thyroid carcinoma than those in thyroid adenoma (P < 0.01). High PRL-3,CD-68 or D2-40 was associated with lymphatic metastasis in patients with papillary thyroid carcinoma(P<0.01).Conclusion The expression levels of PRL-3,CD-68 and D2-40 are positively cor-related in papillary thyroid carcinoma,and they are related to invasion and lymphangiogenesis of papillary thyroid carcinoma.关键词
甲状腺乳头状癌/PRL-3/肿瘤相关巨噬细胞/淋巴管生成Key words
papillary thyroid carcinoma/phosphatase of regenerating liver-3/tumor associated macro-phages/lymphangiogenesis引用本文复制引用
孙振华,蒋华平,陶文华..甲状腺乳头状癌中PRL-3表达与肿瘤相关巨噬细胞及淋巴管生成的相关性[J].实用医学杂志,2018,34(6):987-990,4.基金项目
镇江市重点研发计划-社会发展课题(编号:SH2015052) （编号:SH2015052）
