实用医学杂志2018，Vol.34Issue(6)：1019-1022,4.DOI:10.3969/j.issn.1006-5725.2018.06.036
肺癌双能量成像、微血管密度和血管内皮生长因子与淋巴结转移的关系
Correlation between dual source CT dual energy imaging indices,microvessel density,vascular endotheli-al growth factor and lymphatic involvement in lung cancer
摘要
Abstract
Objective To explore the correlation between dual energy imaging indices,microvessel densi-ty(MVD),vascular endothelial growth factor(VEGF)and lung cancer lymph nodes metastasis and its practical sig-nificance by applying dual source CT(DSCT)dual energy imaging.Methods 62 cases of non-small cell lung can-cer(NSCLC)were underwent DSCT dual energy imaging and divided into groups with and without lymph node me-tastasis according to the results of pathology.The expressions of MVD and VEGF were detected as well.All the indi-ces were compared between the two groups. Results(1)The differences between the lung cancer lymph node groups in the iodine concentration,normalized iodine concentration(NIC),spectrum curve of arterial phase,MVD and VEGF were statistically significant(P<0.05).(2)The iodine concentration,NIC and spectrum curve of arte-rial phase were positively correlated with MVD and VEGF.Conclusion Iodine concentration,NIC,and spectrum curve of arterial phase of DSCT dual energy imaging can be regarded as part of the important indices for preopera-tive diagnosis of lymph node metastasis of NSCLC.关键词
肺癌/病理学/淋巴转移/体层摄影术,X线计算机Key words
lung cancer/pathology/lymphatic metastasis/tomography X-ray computed引用本文复制引用
顾艳,苗重昌,袁刚,王宗盛,周莹..肺癌双能量成像、微血管密度和血管内皮生长因子与淋巴结转移的关系[J].实用医学杂志,2018,34(6):1019-1022,4.基金项目
江苏省连云港市卫生科技资助项目(编号:ZD201501) （编号:ZD201501）
