西北国防医学杂志2018，Vol.39Issue(2)：87-90,4.DOI:10.16021/j.cnki.1007-8622.2018.02.005
高原相关性血小板改变的机制探讨
New insights into mechanisms of high altitude-associated platelet abnormalities
摘要
Abstract
In recent years,combat missions and non-combat missions of the army have been more and more frequent in the highlands.However,the special geographical environment in highlands will cause a series of damage to the human body,especially cardiovascular systems,respiratory system and hematologic systems,which will threaten the health of soldiers and directly affect the combat effectiveness.Platelets (PLT) are important blood cells.Soldiers entering the highlands always occur changes of PLT levels and functions,in which severe cases can lead to thrombotic disease and thrombocytopenic purpura.Nevertheless,the studies about high altitude-associated PLT abnormalities are scarce and the underlying mechanisms are far from elucidated.Therefore,deep investigations into high altitude-associated PLT abnormalities are the essential steps in preventing PLT-associated diseases,searching for effective intervention measures and improving the life quality of soldiers in highlands.In this article,we will summarize the latest research findings and discuss the potential mechanisms underlying high altitude-associated PLT abnormalities.Finally,we expect to provide new insights into the prevention and treatment of high altitude-associated PLT abnormalities.关键词
高原/血小板/肺/应激/性别Key words
high altitude/platelets/lungs/stress/gender分类
医药卫生引用本文复制引用
杜长虹,宋航,王国威,赵婕,江小瑜,邱义稳,钟大平..高原相关性血小板改变的机制探讨[J].西北国防医学杂志,2018,39(2):87-90,4.基金项目
成都军区“十二五”科研基金资助项目(B14002) （B14002）
