西南国防医药2018，Vol.28Issue(3)：296-299,4.DOI:10.3969/j.issn.1004-0188.2018.03.038
老年社区获得性肺炎住院患者耐药菌感染危险因素分析
Analysis on hazard factors for drug-resistance bacteria infection of CAP of senile ones
孟小蓉 1孙春丽 1王丽平 1张磊 1孟丹丹2
作者信息
- 1. 610500成都,成都医学院第一附属医院老年科
- 2. 绵阳市中心医院药剂科
- 折叠
摘要
Abstract
Objective To explore the distribution behaviors and hazard factors of drug-resistance bacterial infection of Community acquired pneumonia (CAP) senile ones.Methods Retrospective analysis was made on the results of pathogen detection for 261 CAP patients.Logistics regression was applied in analyzing the hazard factors for drug-resistance bacterial infection.Results A total of 135 strains of pathogenic bacteria were separated,among which the top three bacteria were respectively streptococcus pneumoniae (22.72％),klebsiella pneumoniae (19.69％) and streptococcus pneumoniae complicated with mycoplasma pneumoniae (15.15％) for patents aged 65-74,and klebsiella pneumoniae (28.98％),streptococcus pneumoniae (15.94％) and haemophilus influenzae(11.59％) for patients aged ≥ 75.There were 58 strains of drug-resistance bacteria,32 strains of Gram-negative bacteria(55.17％) and 26 strains of Gram-positive bacteria (44.83％),in which streptococcus pneumoniae was the most dominant bacterium (27.59％),followed by klebsiella pneumoniae,haemophilus influenzae,methicillin-resistant staphylococcusaureus and pseudomonas aeruginosa in sequence.The hazard factors clearly correlated to drug-resistance bacterial infection of CAP of the senile ones involved a hospitalization frequency ≥ 3 times per year,long-term bedridden,irregular administration of antibiotics,irregular use of proton-pump inhibitors and a history of cerebral apoplexy.Conclusion There are several hazard factors for drug-resistance bacterial infection of CAP of senile ones.Appropriate and comprehensive assessment and enhanced monitoring can reduce the failure rate of experience-based use of antibiotics and attribute to better prevention and control of drug-resistance bacteria.关键词
老年/住院/社区获得性肺炎/耐药菌/危险因素Key words
aged/hospitalization/CAP/drug-resistance bacteria/hazard factor分类
医药卫生引用本文复制引用
孟小蓉,孙春丽,王丽平,张磊,孟丹丹..老年社区获得性肺炎住院患者耐药菌感染危险因素分析[J].西南国防医药,2018,28(3):296-299,4.
