中国临床药理学与治疗学2018，Vol.23Issue(2)：189-193,5.DOI:10.12092/j.issn.1009-2501.2018.02.014
前列腺素E2辅助球囊应用对足月阴道分娩产妇促宫颈成熟、产程及引产效果的影响
Effects of prostaglandin E2 assisted balloon application on vaginal delivery, cervical ripening and induction of labor in term vaginal delivery
摘要
Abstract
AIM:To study the effects of prostaglandin E2 assisted balloon on the vaginal delivery,cervical ripening and induction of labor in women undergoing full term vaginal delivery.METHODS:Two hundred and thirty cases of full-term mothers who were produced in our hospital from March 2015 to March 2017 were selected as subjects.Two hundred and thirty cases of full-term maternal random number table method were divided into observation group and control group,115 cases in each.Two groups of maternal were fetal heart rate monitoring.Pregnant women of observation group were given dinoprostone suppositories COOK cervical dilatation balloon,while pregnant women of the control group were given COOK cervical dilatation balloon,and placed COOK cervix after balloon.The shrink and fetal heart condition were closely monitored.Labor process,cervical ripening and induction of labor in pregnant women with vaginal delivery were observed.RESULTS:There was no significant difference between the two groups in age,gestational age,primipara number,gestational age,number of gestational age below 37 weeks and Bishop score (P ＞ 0.05).The observation group's success rate of induced labor,Bishop score and Bishop score growth were 79.13％,(8.57 ± 1.20) score and (5.87 ± 1.41) score,respectively,the control group were 64.35％,(7.03 ±0.68) score and (4.35 ±1.10) score,respectively,the observation group was higher than the control group.The observation group's labor time,postpartum hemorrhage,labor,first stage and second stage of labor were (16.92 ± 4.17) h,(203.40±30.78) mL,(6.38±1.77) h,(6.19 ± 1.40) h and (24.37 ± 5.61) min,respectively,the control group were (20.45 ± 3.75) h,(234.94 ±42.04) mL,(7.93 ±1.77) h,(7.08±1.33) h and (34.63 ± 8.18) min,respectively;the observation group was lower than the control group,the difference was statistically significant (P ＜ 0.05).There was no significant difference in the third stage of labor between the two groups (P ＞ 0.05).There was no significant difference in the Apgar score,neonatal asphyxia and neonatal weight between the two groups (P ＞ 0.05).The effective rate of cervical ripening in the observation group was 96.52％,higher than 82.61％ in the control group,and the difference was statistically significant (P ＜ 0.05).CONCLUSION:Prostaglandin E2 assisted balloon can shorten the term vaginal delivery of maternal cervical ripening time as soon as possible to promote cervical ripening,shorten delivery time,improve the success rate,and has no influence on the newborn,it is worthy of clinical application.关键词
COOK球囊/前列腺素E2/促宫颈成熟/引产Key words
COOK balloon/prostaglandin E2/promote cervical ripening/induction of labor分类
医药卫生引用本文复制引用
赵文斌,王学平,陈香军..前列腺素E2辅助球囊应用对足月阴道分娩产妇促宫颈成熟、产程及引产效果的影响[J].中国临床药理学与治疗学,2018,23(2):189-193,5.基金项目
浙江省医药卫生科技计划项目(2015KYB378) （2015KYB378）
