中国临床药理学与治疗学2018，Vol.23Issue(2)：211-216,6.DOI:10.12092/j.issn.1009-2501.2018.02.018
小肠腺癌发病机制研究进展
Research progress in mechanisms of small bowel adenocarcinoma
摘要
Abstract
Small bowel adenocarcinoma (SBA) is a rare malignant tumor with poor prognosis and low overall survival.Researches of recent years have shown that the environmental factors and genetic factors play a role in the development of SBA.In addition,a variety of genetic mutations,DNA methylation,DNA mismatch repair,microsatellite instability and related signal pathways were activated abnormally involved in the occurrence and development of SBA.However,the pathogenesis of SBA is not completely clear and further research should be performed to provide theoretical basis and new ideas for the clinical diagnosis,treatment and prognosis of SBA.关键词
小肠腺癌/致癌因素/分子机制Key words
small bowel adenocarcinoma/pathogenic factors/molecular mechanism分类
医药卫生引用本文复制引用
宋彩霞,马强..小肠腺癌发病机制研究进展[J].中国临床药理学与治疗学,2018,23(2):211-216,6.基金项目
国家自然科学基金(81374019) （81374019）
