中国临床药理学与治疗学2018，Vol.23Issue(2)：235-240,6.DOI:10.12092/j.issn.1009-2501.2018.02.022
抗中性粒细胞胞质抗体相关性小血管炎的机制与治疗进展
Pathogenesis and treatment progress of antineutrophil cytoplasmic antibody-associated vasculitis
余淑媛 1郑麟 1韩飞2
作者信息
- 1. 浙江江山市人民医院风湿免疫科,江山324100,浙江
- 2. 浙江大学医学院附属第一医院肾脏病中心浙江省肾脏病防治技术研究重点实验室,国家中医药管理局三级实验室“肾脏免疫实验室”,杭州310003,浙江
- 折叠
摘要
Abstract
Vasculitis is an autoimmune disease which may cause nonspecific inflammation and necrosis of the blood vessels.According to degree of the vascular involvement,vasculitis divides into small vasculitis,moderate vasculitis and large vasculitis.Antineutrophil cytoplasmic antibody (ANCA) associated vasculitis (AAV) which belongs to the small vasculitis includes granulomatous polyangiitis (GPA) microscopic polyangiitis (MPA) and eosinophilic granulomatous polyangiitis (EGPA).Different organs of the whole body could be involved and the active period is extremely dangerous.Untimely treatment can result in high mortality.This paper briefly reviews the pathogenesis and treatment progress of AAV.关键词
抗中性粒细胞胞质抗体相关性小血管炎/环磷酰胺/利妥昔单抗Key words
vasculitis antineutrophil cytoplasmic antibody-associated (AAV)/cyclophosphamide (CTX)/rituximab (RTX)分类
医药卫生引用本文复制引用
余淑媛,郑麟,韩飞..抗中性粒细胞胞质抗体相关性小血管炎的机制与治疗进展[J].中国临床药理学与治疗学,2018,23(2):235-240,6.
