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内镜黏膜下剥离术衍生技术内镜黏膜下挖除术在消化道神经内分泌肿瘤中的应用

周震宇 王小云 龚镭 唐学军 彭晓斌 吴高珏 胡臻

中国内镜杂志2018,Vol.24Issue(4):85-89,5.
中国内镜杂志2018,Vol.24Issue(4):85-89,5.DOI:10.3969/j.issn.1007-1989.2018.04.018

内镜黏膜下剥离术衍生技术内镜黏膜下挖除术在消化道神经内分泌肿瘤中的应用

Endoscopic submucosal excavation as the derivative technology of endoscopic submucosal dissection for the treatment of intestinal neuroendocrine tumor

周震宇 1王小云 1龚镭 1唐学军 1彭晓斌 1吴高珏 1胡臻1

作者信息

  • 1. 南京医科大学附属无锡二院 消化内科,江苏 无锡 214000
  • 折叠

摘要

Abstract

Objective To investigate the therapeutic effect and safety of ESE (endoscopic submucosalexcavation) as the derivative technology of ESD (endoscopic submucosal dissection) for intestinal Neuroendocrinetumor. Methods A total of 23 lesions diagnosed as Neuroendocrine tumor were treated by ESE. Pathologicaldiagnosis was performed. Reverse events were recorded.Patients were followed up for recurrence andmetastasis. Results Lesions, 0.4 ~ 3.0 cm (medium size 1.0 cm) in diameter,were all resected at one ESE procedure.The operation time was 20 ~ 75 min (medium 30 min). Postoperative bleeding occurred in one case .Initiative fullthickness resection was made in one case due to the violation of muscularis propria layer. 23 cases were histologicallydiagnosed as neuroendocrine tumor, with 21 as G1 and 2 as G2, none as G3. Within 3 gastric neuroendocrine tumors,2 were type 1 and 1 was type 2. All resected samples were free of residual tumor cell in the lateral and basalmargins. Conclusion ESE is safe and efficacious for the treatment of intestinal neuroendocrine tumor.

关键词

消化道/神经内分泌肿瘤/内镜黏膜下挖除术

Key words

digestive tract/neuroendocrine tumor/endoscopic submucosal excavation

分类

医药卫生

引用本文复制引用

周震宇,王小云,龚镭,唐学军,彭晓斌,吴高珏,胡臻..内镜黏膜下剥离术衍生技术内镜黏膜下挖除术在消化道神经内分泌肿瘤中的应用[J].中国内镜杂志,2018,24(4):85-89,5.

基金项目

国家自然科学基金(No:81500467) (No:81500467)

江苏省自然科学基金(No:BK20151116) (No:BK20151116)

江苏省卫生卫计委六个一工程科研项目(No:LGY2017011) (No:LGY2017011)

省十三五科教强卫青年人才 ()

无锡市重点学科胃肠病学(No:ZDXK002) (No:ZDXK002)

无锡市第二人民医院樊代明院士工作站(No:CYR1705) (No:CYR1705)

中国内镜杂志

OACSTPCD

1007-1989

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