中国输血杂志2018，Vol.31Issue(1)：61-63,3.DOI:10.13303/j.cjbt.issn.1004-549x.2018.01.018
120例ABO血型正反定型不符影响因素分析及对策浅析
Analysis on the influencing factors of ABO typing discrepancy in 120 cases and potential counter strategies
摘要
Abstract
Objective To analyze the influencing factors causing ABO typing discrepancy and propose potential counter measures improving the overall performance of ABO blood group typing.Methods We retrospectively analyzed 141679 ABO blood group typing cases filed during 2013-2016 with microcolumn gel technique in our hospital.For those cases with ABO typing discrepancy,according to patients' medical history,pertinent methods were used to determine the ABO blood group.Results We found 120 cases of ABO typing discrepancies during these four years,among these factors influencing ABO typing discrepancies,artificial factors accounted for 10％ (12/120),physiology factors accounted for 16.7％ (20/120),disease factors accounted for 54.2％ (65/120),treatment factors accounted for 16.7％ (20/120) and others accounted for 2.5％ (3/120).Of all the factors,malignancy hematologic disease accounted for 41.2％ (50/120),bone marrow transplantation accounted for 16.7％ (20/120),specimens interference accounted for 13.3％ (16/120),autoantibodies accounted for 12.5％ (15/120) and others accounted for 15.8％ (19/120).Concltsion In this study,ABO typing discrepancies were mainly caused by disease factors (mainly malignancy hematologic disease),treatment factors (mainly bone marrow transplantation),specimens interference factors (including hemolysis,fat,fibrinogen,or dilution).To ensure the safety of clinical blood transfusion,combining disease history with other pertinent experiments to determine ABO blood group is neces关键词
ABO血型鉴定/正反定型不符/输血安全Key words
ABO blood typing/ABO typing discrepancies/transfusion safety分类
医药卫生引用本文复制引用
许桂平,康琼华,李晶晶,高琦,刘志东,邱红春,张罗川,张娟..120例ABO血型正反定型不符影响因素分析及对策浅析[J].中国输血杂志,2018,31(1):61-63,3.基金项目
国家自然科学基金项目(81101318,81601826),重庆市科委基金(cstc2015jcsf10006) （81101318,81601826）
