中国动物传染病学报2018，Vol.26Issue(2)：89-94,6.
非洲猪瘟疫苗研究进展
RECENT PROGRESS ON VACCINE DEVELOPMENT AGAINST AFRICAN SWINE FEVER
摘要
Abstract
African swine fever (ASF) is an acute, hemorrhagic and highly contagious disease. African swine fever virus (ASFV) can infect domestic pigs of all breeds and ages as well as European wild boars with the mortality rate up to 100%. In recent years, the spread of ASF in the Caucasus region, the Russian Federation, and several Eastern European countries poses a huge social and economic threat to the global swine industry. Due to the huge genomic structure and complex immune evasion mechanisms of ASFV, no effective vaccine is currently available against the disease. In this review, research efforts toward the development of effective ASF vaccines is presented including inactivated vaccines, live attenuated vaccines, viral vectored vaccines, DNA vaccines and subunit vaccines.关键词
非洲猪瘟/免疫逃逸/疫苗Key words
African swine fever/immune evasion/vaccine分类
农业科技引用本文复制引用
王西西,陈青,吴映彤,郭晓宇,李金祥..非洲猪瘟疫苗研究进展[J].中国动物传染病学报,2018,26(2):89-94,6.基金项目
国家重点研发计划项目资助(2017YFD0502302) （2017YFD0502302）
