中国现代医学杂志2018，Vol.28Issue(11)：79-83,5.DOI:10.3969/j.issn.1005-8982.2018.011.015
胃癌骨转移患者临床病理特征及预后影响因素分析
Clinical features and prognosis of gastric cancer with bone metastasis
范志松 1邢栋 2左静 1王龙 1齐永霞 3李瑞晓 4吕冬婕5
作者信息
- 1. 河北医科大学第四医院 肿瘤内科,河北 石家庄 050011
- 2. 河北省人民医院 骨一科,河北 石家庄 050051
- 3. 河北省定州市人民医院 肿瘤科,河北 定州 073000
- 4. 河北省邢台市隆尧县医院 胸外肿瘤科,河北 邢台 055350
- 5. 河北医科大学第四医院 放五科,河北 石家庄 050011
- 折叠
摘要
Abstract
Objective To evaluate the clinicopathological characteristics and outcomes of gastric cancer patients with bone metastasis. Methods The subjects were 139 gastric cancer patients who were diagnosed with bone metastasis between 2005 and 2015. The influences of pathological characteristics and clinical treatment on the survival time of the patients were analyzed. Results The common sites of bone metastasis were spine, pelvis and ribs. The median survival time of the gastric cancer patients with bone metastasis was 15.1 months, but the median survival time after diagnosis of bone metastasis was only 5.7 months. Tumor stage, simultaneous bone metastasis or not, chemotherapy and bisphosphonate therapy were the independent prognostic factors for overall survival in the gastric patients with bone metastasis (P < 0.05). Whether received chemotherapy or not after bone metastasis was an independent prognostic factor for patients' survival (P < 0.05). Conclusions Bone metastasis usually occurs in advanced stage of gastric cancer, and indicates poor prognosis. After bone metastasis, accepting chemotherapy can prolong the survival time of the patients. Clinicians should pay more attention and provide active therapy to the gastric cancer patients with bone metastasis.关键词
胃癌/骨转移/临床特征/化疗/预后Key words
gastric cancer/bone metastasis/clinical feature/chemotheropy/prognosis分类
医药卫生引用本文复制引用
范志松,邢栋,左静,王龙,齐永霞,李瑞晓,吕冬婕..胃癌骨转移患者临床病理特征及预后影响因素分析[J].中国现代医学杂志,2018,28(11):79-83,5.
