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血清Hcy对不稳定型心绞痛患者焦虑症发生的影响

刘宁 兰青 文书银

中国现代医学杂志2018,Vol.28Issue(11):98-101,4.
中国现代医学杂志2018,Vol.28Issue(11):98-101,4.DOI:10.3969/j.issn.1005-8982.2018.011.019

血清Hcy对不稳定型心绞痛患者焦虑症发生的影响

Correlation analysis between degree of anxiety and serum homocysteine level in patients with unstable angina

刘宁 1兰青 1文书银1

作者信息

  • 1. 四川省德阳市人民医院 心内科,四川 德阳 618000
  • 折叠

摘要

Abstract

Objective To study the correlation between the degree of anxious state in patients with unstable angina and the serum homocysteine (Hcy) level. Methods Totally 150 patients with unstable angina were included. All patients were tested by the self-assessment lists of anxiety (Self-rating Anxiety Scale, SAS), and divided into non-anxiety group and anxiety group. The serum Hcy level was detected. Results There were 68 patients with anxiety in the 150 patients with unstable angina, accounting for 45.3%. The age, SAS score, disease course and Hcy level in the anxiety group were significantly different from that in the patients without anxiety (P < 0.05). Prolonged disease course and increased Hcy level were the independent risk factors for anxiety of the patients with unstable angina (P < 0.05). The Hcy levels and proportion of HH in the mild group were statistically lower than those in the moderate and severe groups (P < 0.05). The Hcy level and proportion of hyperhomocysteinemia in the moderate group were significantly lower than those in the severe group (P < 0.05). Correlation analysis showed that Hcy level increased with the increase of SAS score (P < 0.05). Conclusions Hcy level is a risk factor for anxiety in the patients with unstable angina, and is correlated with the severity of anxiety. The unstable angina patients with elevated serum Hcy level should be closely watched for the emotional changes.

关键词

不稳定型心绞痛/焦虑/同型半胱氨酸

Key words

unstable angina/anxiety/homocysteine

分类

医药卫生

引用本文复制引用

刘宁,兰青,文书银..血清Hcy对不稳定型心绞痛患者焦虑症发生的影响[J].中国现代医学杂志,2018,28(11):98-101,4.

中国现代医学杂志

OACSTPCD

1005-8982

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