中国药房2018，Vol.29Issue(2)：145-151,7.DOI:10.6039/j.issn.1001-0408.2018.02.01
全球抗菌药物使用监测现状的循证评价
Evidence-based Evaluation on the Current Status of Global Antibacterial Use Surveillance
摘要
Abstract
OBJECTIVE:To provide evidence-based basis for the continuous improvement of antibacterial use surveillance in China.METHODS:Retrieving from 3 biomedical literature databases as Medline,Embase,Cochrane Library,48 health administrative departments and academic institutions,relevant literatures on antibacterial surveillance networks/ projects were acquired and extracted,including basic information,data collection,analysis and reporting methods,etc.Descriptive analysis method was adopted to analyze the status quo of global antibacterial surveillance networks/projects.RESULTS:A total of 21 literatures were included,involving 16 antibacterial surveillance networks/projects.Among them,there were 3 international projects and 13 national projects,mainly in European (countries) (56.25％,9/16).Sixteen antibacterial surveillance networks/projects were established to monitor and compare the use of antibacterials,analyze the antibacterial use trend and its correlation with bacterial resistance,and evaluate implementation effect of antibacterial management policy.The responsible agencies were mainly the health administrative departments,and the funding agencies were mainly related government departments.Hospital and community were main surveillance objects.There were 2 surveillance networks/projects for antibacterial use in children,and 6 surveillance networks/projects contained medication data of children.Only Strama in Sweden alone analyzed medication data in children.Fourteen surveillance networks/projects promulgated data collection methods or contents;data collection was mainly based on active reporting and involved the data of drug use/consumption and population/ patient.Except for ESAC-Net,ARPEC,NAUSP,data validation method was not mentioned in other surveillance networks/projects.Data analysis was most common in medical institutions and antibacterial categories,and defined daily dose was the most commonly used statistical indicators of antibacterial consumption.Ten surveillance networks/projects promulgated surveillance reports which were mostly published annually.CONCLUSIONS:Antibacterial surveillance have been widely operated worldwide.But there is a lack of monitoring and analysis of antibacterial use in special population including children.In addition,data validation is the weak link of antibacterial surveillance,so the quality of data collection still need to be improved.关键词
抗菌药物/使用/监测/循证评价Key words
Antibacterial/Use/Surveillance/Evidence-based evaluation分类
医药卫生引用本文复制引用
曾力楠,张祚洁,张伶俐,黄亮,归舸..全球抗菌药物使用监测现状的循证评价[J].中国药房,2018,29(2):145-151,7.基金项目
国家自然科学基金青年科学基金项目(No.71503177) （No.71503177）
国家自然科学基金面上项目(No.81373381)教育部长江学者创新团队基金(No.IRT0935)、国际合理用药网络中国中心组高风险用药人群药物管理组 （No.81373381）
