中国药理学通报2018，Vol.34Issue(4)：445-449,5.DOI:10.3969/j.issn.1001-1978.2018.04.001
人类免疫缺陷病毒动物模型在相关神经病变的研究应用
Human immunodeficiency virus animal models and related neuropathy study
摘要
Abstract
Human immunodeficiency virus(HIV) infection may result in serious impairment of the immune system in HIV-posi-tive patients. Both HIV productions and highly active antiretrovi-ral therapy (HAART) drugs can cause neuropathy, including the HIV associated neurocognitive disorders (HAND) and the peripheral neuropathy. Several animal models have been devel-oped in an attempt to study the mechanisms of HIV relative neu-ropathies. This review focuses on researching HIV-1 associated neuropathies by application of HIV-1 animal models.关键词
人免疫缺陷病毒/人免疫缺陷病毒动物模型/神经认知功能障碍综合征/外周神经病变/神经病理痛/神经炎症Key words
human immunodeficiency virus/HIV-1 animal model/HIV associated neurocognitive disorders/peripheral neu-ropathy/neuropathic pain/neuroinflammation分类
医药卫生引用本文复制引用
易智华,周聪发,何雪莹,梁尚栋..人类免疫缺陷病毒动物模型在相关神经病变的研究应用[J].中国药理学通报,2018,34(4):445-449,5.基金项目
国家自然科学基金资助项目(No 31560276,81570735) （No 31560276,81570735）
江西省科技支撑计划 - 社会发展支撑计划重点项目(No 20151BBG70250) （No 20151BBG70250）
江西省自然科学基金资助项目(No 20142BAB205028) （No 20142BAB205028）
江西省教育厅基金资助项目(No GJJ14319) （No GJJ14319）
