中国医学前沿杂志（电子版）2018，Vol.10Issue(2)：74-76,3.DOI:10.12037/YXQY.2018.02-16
糖尿病和非糖尿病患者应用罗库溴铵对肌肉松弛效应的影响
The effect of Rocuronium bromide on muscle relaxation in diabetic and non-diabetic patients
摘要
Abstract
Objective To explore the effect of Rocuronium bromide on muscle relaxation in patients with diabetic or non-diabetic. Method From February 2015 to January 2017, 45 patients with diabetes in Baoding First Central Hospital, who were adopted the line colorectal surgery and as the diabetes group, at the same time, 45 patients with non-diabetic were adopted colorectal surgery as the non-diabetic group. Anesthesia induction was a single intravenous injection of Rocuronium bromide 0.6 mg/kg, the onset time of Rocuronium bromide and rate of intravenous drip from 30 minutes to 4 hours in the two groups were observed, and continuous muscle relaxation monitoring until the end of operation, muscle relaxation recovery index and recovery time of the two groups were observed and compared. Result The rate of continuous intravenous infusion was gradually decreased from 30 minutes to 4 hours in the diabetic group, compared with the non-diabetic group, there was no significant difference (P<0.05). There was no significant difference in onset time and recovery index T1 25%~75%between the two groups after continuous intravenous infusion of Rocuronium bromide (P>0.05). After stopping infusion, the recovery time of T1in the diabetic group to 90% was longer than that in the non-diabetic group (P<0.05). No obvious adverse reactions were found in the diabetic group and the non-diabetic group. Conclusion The effect of Rocuronium bromide on muscle relaxation is significantly different in patients with diabetes and non-diabetic, and the muscle relaxation effect is more obvious in diabetic patients.关键词
罗库溴铵/糖尿病/肌肉松弛Key words
Rocuronium bromide/Diabetes mellitus/Muscle relaxation引用本文复制引用
李爱军,白艳辉,张世明..糖尿病和非糖尿病患者应用罗库溴铵对肌肉松弛效应的影响[J].中国医学前沿杂志（电子版）,2018,10(2):74-76,3.基金项目
陕西省社会发展攻关计划项目(S2014SF4268) （S2014SF4268）
