摘要
Abstract
Objective To analyze the risk factors of hypoxemia after thoracotomy in patients with acute dissecting aneurysm of aorta. Method The clinical datas of 89 patients with acute dissecting aneurysm of aorta who underwent thoracotomy in our hospital from February 2009 to December 2014 were retrospectively analyzed, they were divided into hypoxemia group and non-hypoxemia group according to whether they had postoperative hypoxemia. The clinical datas of the two groups were analyzed and compared, and multivariate Logistic regression was used to analyze the risk factors of hypoxemia. Result 42 cases of hypoxemia occurred in 89 patients, the incidence was 47.2%. There were 7 cases of death, the mortality rate was 7.9%, hypoxemia group had a higher mortality rate than non-hypoxemia group (11.9%︰4.3%), but there was no significant difference (P>0.05). Multivariate Logistic regression analysis showed that independent risk factors of hypoxemia in patients with acute dissecting aneurysm of aorta after thoracotomy were body mass index > 25 kg/m2(OR = 2.643),intraoperative and postoperative blood transfusion volume ≥ 8 U (OR=3.083),postoperative blood glucose levels>11.1 mmol/L(OR=2.973),preoperative PaO2/FiO2≤300 mmHg(OR=3.193), deep hypothermic circulatory arrest(OR = 2.863),the differences were significant(P < 0.05).Conclusion For acute dissecting aneurysm of aorta patients with overweight, and obesity, low PaO2/FiO2before operation, early intervention should be given before operation, and to avoided during and after surgery, and should actively control the postoperative stress hyperglycemia, to reduce the occurrence of hypoxemia.关键词
急性主动脉夹层动脉瘤/开胸术/低氧血症/危险因素Key words
Acute dissecting aneurysm of aorta/Thoracotomy/Hypoxemia/Risk factors