浙江医学2018，Vol.40Issue(3)：240-242,247,后插1,5.DOI:10.12056/j.issn.1006-2785.2018.40.3.2017-656
早期乳腺癌患者保乳术后三维适形、调强放疗和混合调强3种放疗计划的比较分析
Comparison of 3D-conformal radiotherapy, intensity-modulated radiotherapy and hybrid intensity-modulated radiotherapy for breast cancer patients following breast-conserving surgery
邱凌云 1宋涛 1贾勇士1
作者信息
- 1. 310014 杭州医学院附属人民医院放疗科
- 折叠
摘要
Abstract
Objective To compare 3D-conformal radiotherapy (3D-CRT),intensity-modulated radiotherapy (IMRT) and hybrid intensity-modulated radiotherapy (h-IMRT) for breast cancer patients following breast-conserving surgery.Methods Thirty patients with breast cancer (15 left,15 right) receiving breast-conserving surgery were recruited.The therapeutic plans 3D-CRT,IMRT and h-IMRT were made respectively.The dose-volume parameters,including target coverage,homogeneity,doses to the organs at risk (heart,the contralateral lung and others) were compared among three plans.The mean doses of organs at risk were also evaluated.Results The IMRT and h-IMRT plans provided lower V105％(％) dose and better mean dose than 3D-CRT plans (left side:F=6.45,11.3,right side:F=9.57,10.3;P＜0.05).The ipsilateral lung received a volume of 20 Gy and 30 Gy for h-IMRT,which was significantly less than that for 3D-CRT or IMRT (left side:F=7.98,9.56,right side:F=5.89,6.54;P＜0.05).The heart received V5Gy (％) dose for 3D-CRT,which was superior to those of IMRT and h-IMRT (left side:F=3.8,P＜ 0.05).The low volume dose distribution of V30Gy (％) in heart for h-IMRT was better than that for 3D-CRT and IMRT (left side:F=13.5,P＜0.05).The total MUs of h-IMRT were between 3D-CRT and IMRT (left side:F=10.89,right side:12.34;P＜0.05).Conclusion Compared with two other techniques,additional improvements can be obtained by using h-IMRT.h-IMRT plan is more appropriate for early breast cancer patients after breast-conserving surgery.关键词
乳腺癌/调强放疗/混合调强放疗/同步补量照射技术Key words
Breast cancer/Intensity-modulated radiotherapy/Hybrid intensity-modulated radiotherapy/Simultaneous integrated boost引用本文复制引用
邱凌云,宋涛,贾勇士..早期乳腺癌患者保乳术后三维适形、调强放疗和混合调强3种放疗计划的比较分析[J].浙江医学,2018,40(3):240-242,247,后插1,5.
