中医药学报2017,Vol.45Issue(6):113-118,6.
女贞子中齐墩果酸提取制备与含量测定方法的研究进展
Extraction and Determination Methods of Oleanolic Acid in Ligustrum lucidum Ait.
摘要
Abstract
Ligustrum lucidum Ait.has been used for at least 2000 years as a common herbs to nourish liver and kidney in Chinese materia medica.2015 edition of Pharmacopoeia records 115 kinds of Chinese patent medicines containing L.lucidum Ait.,which are used widely in clinical application.Oleanolic Acid(OA) having a variety of pharmacological activities,especially on liver,is one of the main active ingredients in L.lucidum Ait.,and it is regarded as the quality controlling index of Ligustrum lucidum Ait.In the last ten years,new extraction technologies and methods for the determination of OA were put forward.So this study summarized the research progress of extraction and determination methods of OA in L.lucidum Ait.In recent years,providing reference for the reform of Chinese patent medicines and providing theoretical foundation for its quality control.关键词
女贞子/齐墩果酸/提取纯化/含量测定Key words
Ligustrum lucidum Ait./Oleanolic acid/Extraction and purification/Quantitative determination分类
医药卫生引用本文复制引用
常艳丽,折改梅,李鹏跃,何婷,赵怡程,陈晓怡,白少娟,王乐,王秀环,刘斌..女贞子中齐墩果酸提取制备与含量测定方法的研究进展[J].中医药学报,2017,45(6):113-118,6.基金项目
国家自然科学基金项目(81573692) (81573692)
北京中医药大学自主课题项目(2015-JYB-JSMS024) (2015-JYB-JSMS024)