摘要
Abstract
Objective:To investigate the effect of Xiaochaihu granule on T lymphocyte subsets and myocardial enzymes in patients with hospital -acquired infectious myocarditis.Methods:104 patients with hospital -acquired infectious myo-carditis were randomly divided into the control group(n=52)and the study group(n=52).The control group was treated with antiviral medicine,nutritional myocardium,and immunostimulant;on which basis,the study group was also treated with Xiaochaihu granules.The treatment course was four weeks.The levels of T lymphocyte subsets,myocardial enzymes and troponin I and troponin T were measured before and after the treatment,and the clinical efficacy and medi-cation safety were compared.Results:The levels of CI,EF,CO, SV,CD3 +,CD4 +,CD8 +and NK were increased after the treatment,whereas the levels of LDH,CK-MB,CK,α-HBDH,troponin T,and troponin T were decreased (P<0.05);of which the increasing levels and decreasing levels of the study group was more significantly than those of the control group(P<0.05).The effective rate of the control group was 75.00%, which was significantly lower than 90.39%of the study group(P<0.05).There was no significant difference in the incidence of adverse reactions be-tween the two groups(P>0.05).Conclusion:Xiaochaihu granule has definite effect on patients with hospital -acquired infectious myocarditis,which can help to reduce myocardial injury and enhance immune function,and the medication is safe and is worthy to be widely popularized.关键词
小柴胡颗粒/感染性心肌炎/T淋巴细胞亚群/心肌酶Key words
Xiaochaihu granule/Hospital-acquired infectious myocarditis/T lymphocyte subsets/Myocardial enzymes分类
医药卫生
