成都中医药大学学报2018，Vol.41Issue(1)：30-33,4.DOI:10.13593/j.cnki.51-1501/r.2018.01.030
大花龙胆治疗急性咽炎的有效部位研究
Study on Effective Fraction of Gentiana Szechenyii in Treatment of Acute Pharyngitis
摘要
Abstract
Objective:To screen the effective fraction of Gentiana Szechenyii through comparing their effects of various polar regions in treatment of acute pharyngitis rats.Methods:The effects of different polar regions on the histopathological morphology and serum IL-10 and TNF-α expression in rats were observed by using 25％ ammonia chemical stimulation to the rats acute pharyngitis modeL Results:The rats throat mucosa of model control group appeared obvious pathological changes,compared with model control group,Gentiana Szechenyii different polar parts group of rats with acute pharyngitis had different degrees of improvement,in which the pharyngeal lesions were repaired obviously,which could reduce the levels of IL-10、TNF-α in rat serum (P ＜0.01).Conclusions:The effective components of Gentiana Szechenyii to treat acute pharyngitis were focused on the n-butanol fraction.The separation and screening of n-butanol fraction was studied for further explore of its pharmacodynamic base.关键词
大花龙胆/急性咽炎/有效部位Key words
Gentiana Szechenyii/Acute pharyngitis/Effective fraction分类
医药卫生引用本文复制引用
张彩虹,古锐,韦婷,曾勇,胡明勋,陈玉峰,张静波..大花龙胆治疗急性咽炎的有效部位研究[J].成都中医药大学学报,2018,41(1):30-33,4.基金项目
国家自然科学基金青年基金项目(81603395) （81603395）
