成都中医药大学学报2018，Vol.41Issue(1)：46-49,4.DOI:10.13593/j.cnki.51-1501/r.2018.01.046
大黄芪汤联合化疗抑制晚期非小细胞肺癌新增转移的回顾性临床研究
Clinical Research on Dahuangqi Decoction Combined with Chemotherapy Inhibiting New Metastasis for Advanced Non-Small Lung Carcinoma
摘要
Abstract
Objective:To research the inhibitory effect of Dahuangqi Decoction combined with chemotherapy on new metastasis of advanced Non-Small Lung carcinoma.Methods:Between April,2016,and April,2017,57 patients were assigned,29 to Dahuangqi Decoction combined with chemotherapy and 28 to chemotherapy.The primary end point was objective response rate (ORR),time to metastasis (TTM),and the incidence of new metastasis.Results:In the period of chemotherapy,the ORR of was 35％ in the treatment group and 33 ％ in the control group (P ＞ 0.05),and the median TTM was significantly longer in the treatment group than in the control group (7.8 vs.4.3 months HR:0.41;P ＜0.01).The incidence of new metastasis was less in treatment group than in control group (16 [55％] of 29 patients,24 [86％] of 28 patients,P ＜ 0.05).Conclusion:It is affirmative to inhibit new metastasis when treating the advanced Non-Small Lung carcinoma with Dahuangqi Decoction and chemotherapy.关键词
肺癌/人参/黄芪/化疗/转移Key words
Lung carcinoma/Ginseng/Astragalus/Chemotherapy/Metastasis分类
医药卫生引用本文复制引用
熊绍权,罗秋月,李亚玲,姚德祎,吕盼盼,何成诗..大黄芪汤联合化疗抑制晚期非小细胞肺癌新增转移的回顾性临床研究[J].成都中医药大学学报,2018,41(1):46-49,4.基金项目
国家自然科学基金面上项目资助项目(81573968) （81573968）
四川省中医药管理局资助项目(2014A026) （2014A026）
四川省教育厅项目(13ZA0277) （13ZA0277）
