临床口腔医学杂志2018,Vol.34Issue(4):205-208,4.DOI:10.3969/j.issn.1003-1634.2018.04.005
梯度脱矿自体牙配合Bio-Oss骨粉用于牙槽骨缺损修复的研究
Study on the repair of alveolar bone defect using gradient demineralization autogenous teeth associating with Bio?Oss bone powder
摘要
Abstract
Objective:To study the effect of gradient demineralized autogenous teeth combined with Bio-Oss bone powder in the repairing the alveolar bone defects.Methods:Animal models of mandible defectin rabbits were established,ti-tanium nail fixation with autogenous bone,autogenous teeth,and gradient demineralized autogenous teeth combined with Bio-Oss bone powder used to repair alveolar bone defects.After 12 weeks,animals were sacrificed for sampling,imaging and histo-logical observation.Results:Twelve weeks after operation,all grafts and bone tissue sealing were good,without loose and fall off.X-rays showed that the bone density and height around the titanium nail in different experimental groups have different degrees of change. Histology studies suggested that the interface between graft and bone tissue in different experimental groups have different degrees of vascularization and new bone formation.Conclusion:Internal fixation of autogenous teeth with titanium nails can be used to repair bone defect,and the effect of different degrees of demineralization autogenous teeth is different.关键词
脱矿牙/Bio-Oss骨粉/骨缺损修复Key words
Demineralized teeth/Bio-Oss bone powder/Bone defect repair分类
医药卫生引用本文复制引用
吕娟,高子龙,朱友家,沈昕,黄闽,王阅春..梯度脱矿自体牙配合Bio-Oss骨粉用于牙槽骨缺损修复的研究[J].临床口腔医学杂志,2018,34(4):205-208,4.基金项目
湖北省自然科学基金(2017CFB776) (2017CFB776)